Pentoxifylline Alleviates Perinatal Hypoxic-Ischemia-Induced Short-term Memory Impairment by Suppressing Apoptosis in the Hippocampus of Rat Pups

Pentoxifylline Alleviates Perinatal Hypoxic-Ischemia-Induced Short-term Memory Impairment by Suppressing Apoptosis in the Hippocampus of Rat Pups

Purpose: Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurologic morbidity in infants and children. We investigated the effects of pentoxifylline, a methylxanthine derivative and type-4 phosphodiesterase inhibitor, on short-term memory and apoptotic neurona...

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Detalhes bibliográficos
Principais autores: Je Hoon Park, Sung Eun Kim, Jun Jang Jin, Han Sung Choi, Chang Ju Kim, Il Gyu Ko
Formato: Artigo
Idioma:English
Publicado em: Korean Continence Society 2016-06-01
coleção:International Neurourology Journal
Assuntos:
Hypoxia-Ischemia
Pentoxifylline
Phosphodiesterase-4 Inhibitors
Memory
Cyclic AMP
Apoptosis
Acesso em linha:http://www.einj.org/upload/pdf/inj-1632532-266.pdf

Internet

http://www.einj.org/upload/pdf/inj-1632532-266.pdf

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