Serum from morbidly obese patients affects melanoma cell behavior in vitro
Abstract Here we examined whether serum from obese patients could create a growth-enhancing microenvironment that alters gene expression in BRAF- and NRAS-mutated melanoma cell lines. SK-Mel-28 (BRAF-mutated) and Sk-Mel-147 (NRAS-mutated) cells were treated with pooled serum from 10 severely obese p...
Main Authors: | Débora Mocellin, Letícia de Oliveira Souza Bratti, Adny Henrique Silva, Laura Sartori Assunção, Iara Fabricia Kretzer, Fabíola Branco Filippin-Monteiro |
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Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2022-06-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100583&lng=en&tlng=en |
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