Microbiome in liver diseases: update from a clinical perspective

There is a constant progress in our understanding of gut-microbiota-liver axis. In this review, we provide the readers with a summary of the recent knowledge related to the field of microbiome and liver disease. For this purpose, we reviewed and selected some of the most distinct studies published b...

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Main Authors: A. Link, H. Tilg
Format: Article
Language:English
Published: Verduci Editore 2020-06-01
Series:Microbiota in Health and Disease
Subjects:
Online Access:https://www.microbiotajournal.com/wp-content/uploads/sites/7/2020/06/e297-Microbiome-in-liver-diseases-update-from-a-clinical-perspective.pdf
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author A. Link
H. Tilg
author_facet A. Link
H. Tilg
author_sort A. Link
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description There is a constant progress in our understanding of gut-microbiota-liver axis. In this review, we provide the readers with a summary of the recent knowledge related to the field of microbiome and liver disease. For this purpose, we reviewed and selected some of the most distinct studies published between April 2019 and March 2020 with the focus on clinical and translational work related to human data. This overview would allow the readers to obtain the current comprehensive insights in the liver-microbiota field. The work includes the summary of associational studies to obesity, non-alcoholic fatty liver disease, liver cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis and finally hepatocellular carcinoma. The work summarizes also recent interventional studies related to liver disease in particular for the treatment of non-alcoholic fatty liver disease and steatohepatitis.
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spelling doaj.art-d8eedb635d50444fa5f5ec723646160d2022-12-21T22:42:33ZengVerduci EditoreMicrobiota in Health and Disease2704-88452020-06-01210.26355/mhd_20206_297297Microbiome in liver diseases: update from a clinical perspectiveA. Link0H. Tilg1Department of Gastroenterology, Hepatology and Infectious Diseases, Section of Molecular Gastroenterology and Microbiota-associated Diseases, Otto-von-Guericke University, Magdeburg, GermanyDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, AustriaThere is a constant progress in our understanding of gut-microbiota-liver axis. In this review, we provide the readers with a summary of the recent knowledge related to the field of microbiome and liver disease. For this purpose, we reviewed and selected some of the most distinct studies published between April 2019 and March 2020 with the focus on clinical and translational work related to human data. This overview would allow the readers to obtain the current comprehensive insights in the liver-microbiota field. The work includes the summary of associational studies to obesity, non-alcoholic fatty liver disease, liver cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis and finally hepatocellular carcinoma. The work summarizes also recent interventional studies related to liver disease in particular for the treatment of non-alcoholic fatty liver disease and steatohepatitis.https://www.microbiotajournal.com/wp-content/uploads/sites/7/2020/06/e297-Microbiome-in-liver-diseases-update-from-a-clinical-perspective.pdflivermicrobiotamicrobiomefmtnafldliver cirrhosisclinical trials.
spellingShingle A. Link
H. Tilg
Microbiome in liver diseases: update from a clinical perspective
Microbiota in Health and Disease
liver
microbiota
microbiome
fmt
nafld
liver cirrhosis
clinical trials.
title Microbiome in liver diseases: update from a clinical perspective
title_full Microbiome in liver diseases: update from a clinical perspective
title_fullStr Microbiome in liver diseases: update from a clinical perspective
title_full_unstemmed Microbiome in liver diseases: update from a clinical perspective
title_short Microbiome in liver diseases: update from a clinical perspective
title_sort microbiome in liver diseases update from a clinical perspective
topic liver
microbiota
microbiome
fmt
nafld
liver cirrhosis
clinical trials.
url https://www.microbiotajournal.com/wp-content/uploads/sites/7/2020/06/e297-Microbiome-in-liver-diseases-update-from-a-clinical-perspective.pdf
work_keys_str_mv AT alink microbiomeinliverdiseasesupdatefromaclinicalperspective
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