A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl<sup>−</sup> Transport in Ca<sup>2+</sup> Dynamics

A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl<sup>−</sup> Transport in Ca<sup>2+</sup> Dynamics

The establishment and maintenance of ion gradients between the interior of lysosomes and the cytosol are crucial for numerous cellular and organismal functions. Numerous ion transport proteins ensure the required variation in luminal concentrations of the different ions along the endocytic pathway t...

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Bibliographic Details
Main Authors:	Rosario Astaburuaga, Orlando Daniel Quintanar Haro, Tobias Stauber, Angela Relógio
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Cells
Subjects:	mathematical modelling lysosomal homeostasis slowly voltage-gated chloride transport lysosomal ca<sup>2+</sup> dynamics
Online Access:	https://www.mdpi.com/2073-4409/8/10/1263

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