S100A9 extends lifespan in insulin deficiency
Insulin replacement is a valuable therapy for insulin deficiency, however, other therapies are being investigated to restore metabolic homeostasis. Here, the authors identify S100A9 as a leptin induced circulating cue that improves glucose and lipid homeostasis and extends survival in insulin defici...
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Bibliographic Details
Main Authors: |
Giorgio Ramadori,
Sanda Ljubicic,
Serena Ricci,
Despoina Mikropoulou,
Xavier Brenachot,
Christelle Veyrat-Durebex,
Ebru Aras,
Rafael M. Ioris,
Jordi Altirriba,
Elisabeth Malle,
Dirk Foell,
Thomas Vogl,
Roberto Coppari |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2019-08-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-019-11498-x
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