Diabetes Mellitus Is a Strong Independent Negative Prognostic Factor in Patients with Brain Metastases Treated with Radiotherapy

Diabetes Mellitus Is a Strong Independent Negative Prognostic Factor in Patients with Brain Metastases Treated with Radiotherapy

Background: Brain metastases (BM) cause relevant morbidity and mortality in cancer patients. The presence of cerebrovascular diseases can alter the tumor microenvironment, cellular proliferation and treatment resistance. However, it is largely unknown if the presence of distinct cerebrovascular risk...

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Bibliographic Details
Main Authors: Seong Jeong, Soniya Poudyal, Sabine Klagges, Thomas Kuhnt, Kirsten Papsdorf, Peter Hambsch, Johannes Wach, Erdem Güresir, Franziska Nägler, Alexander Rühle, Nils H. Nicolay, Clemens Seidel
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
brain metastasis
radiotherapy
systemic therapy
diabetes mellitus
vascular risk factors
vascular comorbidities
Online Access:https://www.mdpi.com/2072-6694/15/19/4845

Internet

https://www.mdpi.com/2072-6694/15/19/4845

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