Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy

Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy

Pathological angiogenesis is a major cause of irreversible blindness in individuals of all age groups with proliferative retinopathy (PR). Mononuclear phagocytes (MPs) within neovascular areas contribute to aberrant retinal angiogenesis. Due to their cellular heterogeneity, defining the roles of MP...

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Main Authors: Zhiping Liu, Huidong Shi, Jiean Xu, Qiuhua Yang, Qian Ma, Xiaoxiao Mao, Zhimin Xu, Yaqi Zhou, Qingen Da, Yongfeng Cai, David J.R. Fulton, Zheng Dong, Akrit Sodhi, Ruth B. Caldwell, Yuqing Huo
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-12-01
Series:JCI Insight
Subjects:
Angiogenesis
Ophthalmology
Online Access:https://doi.org/10.1172/jci.insight.160940

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