Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson’s Disease

Aggregation of α-Synuclein, possibly caused by disturbance of proteostasis, has been identified as a common pathological feature of Parkinson’s disease (PD). However, the initiating events of aggregation have not been fully illustrated, and this knowledge may be critical to understanding the disease...

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Bibliographic Details
Main Authors: Deqiang Han, Wei Zheng, Xueyao Wang, Zhiguo Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00045/full

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