Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson’s Disease
Aggregation of α-Synuclein, possibly caused by disturbance of proteostasis, has been identified as a common pathological feature of Parkinson’s disease (PD). However, the initiating events of aggregation have not been fully illustrated, and this knowledge may be critical to understanding the disease...
Main Authors: | Deqiang Han, Wei Zheng, Xueyao Wang, Zhiguo Chen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-03-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fncel.2020.00045/full |
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