Endobronchial mucosal nodular lesions in allergic bronchopulmonary aspergillosis

Bronchoscopic findings often show mucoid impaction in patients with allergic bronchopulmonary aspergillosis (ABPA); however, endobronchial mucosal nodular lesions have not been reported. We herein present the first such case of a 52-year-old woman with ABPA with endobronchial mucosal nodular lesions...

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Bibliographic Details
Main Authors: Fumiya Nihashi, Toshiya Hiramatsu, Tomohiro Uto, Jun Sato, Shiro Imokawa, Takafumi Suda
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Respiratory Medicine Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007119303223
Description
Summary:Bronchoscopic findings often show mucoid impaction in patients with allergic bronchopulmonary aspergillosis (ABPA); however, endobronchial mucosal nodular lesions have not been reported. We herein present the first such case of a 52-year-old woman with ABPA with endobronchial mucosal nodular lesions. The endobronchial lesions were located in the orifice of the mucoid impaction, and disappeared after 4 weeks of treatment with prednisolone and itraconazole. Aspergillus fumigatus was cultured from bronchial lavage fluid collected from the site of mucoid impaction. Based on these clinical findings, we speculate that the bronchial lesions were caused by an inflammatory and allergic reaction to Aspergillus antigens. Keywords: Aspergillus fumigatus, Eosinophilic granulomatosis with polyangiitis, Eosinophilic pneumonia, Mucoid impaction
ISSN:2213-0071