ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES
In the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst activation, being applied to several types of rea...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422019000400425&lng=en&tlng=en |
| _version_ | 1818505348041932800 |
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| author | Fernanda G. Finelli Bruno M. da S. Santos Lívia C. R. M. da Frota |
| author_facet | Fernanda G. Finelli Bruno M. da S. Santos Lívia C. R. M. da Frota |
| author_sort | Fernanda G. Finelli |
| collection | DOAJ |
| description | In the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst activation, being applied to several types of reactions, in a rather generic and predictable way and providing high enantioselectivities. This tutorial review presents the evolution of this area through a brief discussion on all generic modes of activation previously systematized in the literature: activation via enamine, iminium ion, hydrogen-bonding, counterion, SOMO, photoredox, carbene and phase-transfer, and the recent advances in the area. |
| first_indexed | 2024-12-10T21:49:27Z |
| format | Article |
| id | doaj.art-d8fc6aa41cdc44d99d05f817455b3f86 |
| institution | Directory Open Access Journal |
| issn | 1678-7064 |
| language | English |
| last_indexed | 2024-12-10T21:49:27Z |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-d8fc6aa41cdc44d99d05f817455b3f862022-12-22T01:32:15ZengSociedade Brasileira de QuímicaQuímica Nova1678-706442442544610.21577/0100-4042.20170334S0100-40422019000400425ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTESFernanda G. FinelliBruno M. da S. SantosLívia C. R. M. da FrotaIn the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst activation, being applied to several types of reactions, in a rather generic and predictable way and providing high enantioselectivities. This tutorial review presents the evolution of this area through a brief discussion on all generic modes of activation previously systematized in the literature: activation via enamine, iminium ion, hydrogen-bonding, counterion, SOMO, photoredox, carbene and phase-transfer, and the recent advances in the area.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422019000400425&lng=en&tlng=enasymmetric catalysisorganocatalysismode of activationorganocascadecontinuous-flow |
| spellingShingle | Fernanda G. Finelli Bruno M. da S. Santos Lívia C. R. M. da Frota ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES Química Nova asymmetric catalysis organocatalysis mode of activation organocascade continuous-flow |
| title | ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES |
| title_full | ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES |
| title_fullStr | ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES |
| title_full_unstemmed | ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES |
| title_short | ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES |
| title_sort | organocatalise enantiosseletiva evolucao e aspectos recentes |
| topic | asymmetric catalysis organocatalysis mode of activation organocascade continuous-flow |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422019000400425&lng=en&tlng=en |
| work_keys_str_mv | AT fernandagfinelli organocataliseenantiosseletivaevolucaoeaspectosrecentes AT brunomdassantos organocataliseenantiosseletivaevolucaoeaspectosrecentes AT liviacrmdafrota organocataliseenantiosseletivaevolucaoeaspectosrecentes |