A Customizable Suite of Methods to Sequence and Annotate Cattle Antibodies

A Customizable Suite of Methods to Sequence and Annotate Cattle Antibodies

Studying the antibody response to infection or vaccination is essential for developing more effective vaccines and therapeutics. Advances in high-throughput antibody sequencing technologies and immunoinformatic tools now allow the fast and comprehensive analysis of antibody repertoires at high resol...

Full description

Bibliographic Details
Main Authors:	Kristel Ramirez Valdez, Benjamin Nzau, Daniel Dorey-Robinson, Michael Jarman, James Nyagwange, John C. Schwartz, Graham Freimanis, Angela W. Steyn, George M. Warimwe, Liam J. Morrison, William Mwangi, Bryan Charleston, Marie Bonnet-Di Placido, John A. Hammond
Format:	Article
Language:	English
Published:	MDPI AG 2023-06-01
Series:	Vaccines
Subjects:	antibody discovery IgMAT 10x Genomics antibody sequencing antibody repertoire
Online Access:	https://www.mdpi.com/2076-393X/11/6/1099

Similar Items

Prediction of antigen-responding VHH antibodies by tracking the evolution of antibody along the time course of immunization
by: Tomonari Matsuda, et al.
Published: (2024-01-01)

Editorial: Natural Antibodies in Health and Disease
by: Ana Maria Hernandez, et al.
Published: (2017-12-01)

The porcine antibody repertoire: Variations on the textbook theme
by: John eButler
Published: (2012-06-01)

Obesity Is Associated with an Impaired Baseline Repertoire of Anti-Influenza Virus Antibodies
by: Marwa Abd Alhadi, et al.
Published: (2023-06-01)

Regulatory Approved Monoclonal Antibodies Contain Framework Mutations Predicted From Human Antibody Repertoires
by: Brian M. Petersen, et al.
Published: (2021-09-01)

Prediction of polyspecificity from antibody sequence data by machine learning
by: Szabolcs Éliás, et al.
Published: (2024-04-01)

Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response
by: Xuefeng Niu, et al.
Published: (2020-01-01)

The respiratory syncytial virus (RSV) prefusion F‐protein functional antibody repertoire in adult healthy donors
by: Emanuele Andreano, et al.
Published: (2021-06-01)

Separating clinical antibodies from repertoire antibodies, a path to in silico developability assessment
by: Christopher Negron, et al.
Published: (2022-12-01)

SONAR: A high-throughput pipeline for inferring antibody ontogenies from longitudinal sequencing of B cell transcripts
by: Chaim A Schramm, et al.
Published: (2016-09-01)

Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching
by: Felix Horns, et al.
Published: (2016-08-01)

The astonishing diversity of Ig classes and B cell repertoires in teleost fish
by: Simon eFillatreau, et al.
Published: (2013-02-01)

Advances in the Isolation of Specific Monoclonal Rabbit Antibodies
by: Zaibao Zhang, et al.
Published: (2017-05-01)

High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy
by: Genghao Chen, et al.
Published: (2021-10-01)

Seroprevalence of <it>Toxoplasma gondii </it>infection among horses in Tunisia
by: Boughattas Sonia, et al.
Published: (2011-11-01)

Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies
by: Starlynn C. Clarke, et al.
Published: (2019-01-01)

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease
by: Lisa K. Blum, et al.
Published: (2018-07-01)

Understanding the human antibody repertoire
by: Anthony R Rees
Published: (2020-01-01)

Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies
by: Rachael Keating, et al.
Published: (2020-12-01)

Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies
by: Weihsu C. Chen, et al.
Published: (2018-03-01)

Large-scale antibody immune response mapping of splenic B cells and bone marrow plasma cells in a transgenic mouse model
by: Xiaoli Pan, et al.
Published: (2023-06-01)

Diversity in the Cow Ultralong CDR H3 Antibody Repertoire
by: Jeremy K. Haakenson, et al.
Published: (2018-06-01)

Human Immunoglobulin G Cannot Inhibit Fibrinogen Binding by the Genetically Diverse A Domain of <named-content content-type="genus-species">Staphylococcus aureus</named-content> Fibronectin-Binding Protein A
by: P. Martijn den Reijer, et al.
Published: (2018-04-01)

Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures
by: Alexander M. Sevy, et al.
Published: (2019-12-01)

Phage Display Libraries for Antibody Therapeutic Discovery and Development
by: Juan C. Almagro, et al.
Published: (2019-08-01)

Biannual and Quarterly Comparison Analysis of Agglutinating Antibody Kinetics on a Subcohort of Individuals Exposed to Leptospira interrogans in Salvador, Brazil
by: Jaqueline S. Cruz, et al.
Published: (2022-04-01)

Neutralizing and enhancing monoclonal antibodies in SARS-CoV-2 convalescent patients: lessons from early variant infection and impact on shaping emerging variants
by: Frédéric Coutant, et al.
Published: (2024-12-01)

Landscape of infection enhancing antibodies in COVID-19 and healthy donors
by: Hendra S. Ismanto, et al.
Published: (2022-01-01)

A diverse repertoire of human immunoglobulin variable genes in a chicken B cell line is generated by both gene conversion and somatic hypermutation
by: Philip A. Leighton, et al.
Published: (2015-03-01)

Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment With TNFα Antagonists
by: Anna Vaisman-Mentesh, et al.
Published: (2019-12-01)

Formation of ultralong DH regions through genomic rearrangement
by: Brevin A. Smider, et al.
Published: (2020-06-01)

Antibody repertoire profiling with mimotope arrays
by: Shina Pashova, et al.
Published: (2017-02-01)

PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST
by: Cinque Soto, et al.
Published: (2020-07-01)

Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries
by: Anastas Pashov, et al.
Published: (2019-12-01)

Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis
by: Kazutaka Kitaura, et al.
Published: (2017-05-01)

Standardized IMGT® Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires
by: Susana Magadan, et al.
Published: (2019-11-01)

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies
by: Katherine E. Harris, et al.
Published: (2018-04-01)

Development of a Potent and Protective Germline-Like Antibody Lineage Against Zika Virus in a Convalescent Human
by: Fei Gao, et al.
Published: (2019-10-01)

A strong case for third-party testing
by: Fridtjof Lund-Johansen
Published: (2023-11-01)

Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein
by: Jillian M. DiMuzio, et al.
Published: (2021-08-01)