Toxic Epidermal Necrolyisis and Sepsis
A 63-year-old male patient suffered from myalgia, arthralgia cough and erythematous macules, with confluence to the thorax, limbs, thighs and the scrotum. The erythematous macules evolved to blisters with a positive Nikolsky’s sign. A cutaneous biopsy revealed satellite cell necrosis. Administration...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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SMC MEDIA SRL
2016-11-01
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Series: | European Journal of Case Reports in Internal Medicine |
Subjects: | |
Online Access: | http://ejcrim.com/index.php/EJCRIM/article/view/502 |
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author | Daniela Dias Alves Nulita Lourenço Daniela Franco Eufémio Calmeiro Rosa Silva |
author_facet | Daniela Dias Alves Nulita Lourenço Daniela Franco Eufémio Calmeiro Rosa Silva |
author_sort | Daniela Dias Alves |
collection | DOAJ |
description | A 63-year-old male patient suffered from myalgia, arthralgia cough and erythematous macules, with confluence to the thorax, limbs, thighs and the scrotum. The erythematous macules evolved to blisters with a positive Nikolsky’s sign. A cutaneous biopsy revealed satellite cell necrosis. Administration of immunoglobulins resulted in a favourable evolution of the cutaneous lesions. Toxic epidermal necrolysis (TEN) is a rare and potentially fatal mucocutaneous disease. Early recognition, diagnosis and therapy are of the utmost importance. |
first_indexed | 2024-04-13T06:53:32Z |
format | Article |
id | doaj.art-d8fe2d8af33044548273e53137bb19b6 |
institution | Directory Open Access Journal |
issn | 2284-2594 |
language | English |
last_indexed | 2024-04-13T06:53:32Z |
publishDate | 2016-11-01 |
publisher | SMC MEDIA SRL |
record_format | Article |
series | European Journal of Case Reports in Internal Medicine |
spelling | doaj.art-d8fe2d8af33044548273e53137bb19b62022-12-22T02:57:20ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942016-11-013710.12890/2016_000502179Toxic Epidermal Necrolyisis and SepsisDaniela Dias Alves0Nulita Lourenço1Daniela Franco2Eufémio Calmeiro3Rosa Silva4Internal Medicine Department Hospital Amato Lusitano, Castelo BrancoIntensive Care Department, Hospital Amato Lusitano, Castelo BrancoInternal Medicine Department, Hospital Amato Lusitano, Castelo BrancoInternal Medicine Department, Hospital Amato Lusitano, Castelo BrancoInternal Medicine Department, Hospital Amato Lusitano, Castelo BrancoA 63-year-old male patient suffered from myalgia, arthralgia cough and erythematous macules, with confluence to the thorax, limbs, thighs and the scrotum. The erythematous macules evolved to blisters with a positive Nikolsky’s sign. A cutaneous biopsy revealed satellite cell necrosis. Administration of immunoglobulins resulted in a favourable evolution of the cutaneous lesions. Toxic epidermal necrolysis (TEN) is a rare and potentially fatal mucocutaneous disease. Early recognition, diagnosis and therapy are of the utmost importance.http://ejcrim.com/index.php/EJCRIM/article/view/502Toxic epidermal necrolysisNikolsky’s signerythematous macules. |
spellingShingle | Daniela Dias Alves Nulita Lourenço Daniela Franco Eufémio Calmeiro Rosa Silva Toxic Epidermal Necrolyisis and Sepsis European Journal of Case Reports in Internal Medicine Toxic epidermal necrolysis Nikolsky’s sign erythematous macules. |
title | Toxic Epidermal Necrolyisis and Sepsis |
title_full | Toxic Epidermal Necrolyisis and Sepsis |
title_fullStr | Toxic Epidermal Necrolyisis and Sepsis |
title_full_unstemmed | Toxic Epidermal Necrolyisis and Sepsis |
title_short | Toxic Epidermal Necrolyisis and Sepsis |
title_sort | toxic epidermal necrolyisis and sepsis |
topic | Toxic epidermal necrolysis Nikolsky’s sign erythematous macules. |
url | http://ejcrim.com/index.php/EJCRIM/article/view/502 |
work_keys_str_mv | AT danieladiasalves toxicepidermalnecrolyisisandsepsis AT nulitalourenco toxicepidermalnecrolyisisandsepsis AT danielafranco toxicepidermalnecrolyisisandsepsis AT eufemiocalmeiro toxicepidermalnecrolyisisandsepsis AT rosasilva toxicepidermalnecrolyisisandsepsis |