Genetic Control of Serum Marinobufagenin in the Spontaneously Hypertensive Rat and the Relationship to Blood Pressure

Genetic Control of Serum Marinobufagenin in the Spontaneously Hypertensive Rat and the Relationship to Blood Pressure

BackgroundWe have investigated serum levels of immunoreactive marinobufagenin (MBG) in 16‐ to 20‐week‐old spontaneously hypertensive rats (SHRs)‐A3 and in the normotensive Wistar‐Kyoto (WKY) rat strain in the absence of salt loading, and we have investigated the genetic control of serum MBG. Methods...

Full description

Bibliographic Details
Main Authors:	Renata I. Dmitrieva, Stacy M. Cranford, Peter A. Doris
Format:	Article
Language:	English
Published:	Wiley 2017-10-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:	cholesterol homeostasis endocrinology marinobufagenin Na+/K+‐ATPase sitosterol
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.117.006704

Similar Items

Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia
by: Natalia I. Agalakova, et al.
Published: (2022-03-01)

Endogenous Mammalian Cardiotonic Steroids—A New Cardiovascular Risk Factor?—A Mini-Review
by: Natalia Słabiak-Błaż, et al.
Published: (2021-07-01)

Preeclampsia: Cardiotonic Steroids, Fibrosis, Fli1 and Hint to Carcinogenesis
by: Natalia I. Agalakova, et al.
Published: (2021-02-01)

Urinary Marinobufagenin in Patients with Non-Advanced Chronic Kidney Disease: A Cross-Sectional Study
by: Davide Bolignano, et al.
Published: (2023-07-01)

Marinobufagenin inhibits glioma growth through sodium pump α1 subunit and ERK signaling‐mediated mitochondrial apoptotic pathway
by: Yu‐Long Lan, et al.
Published: (2018-05-01)

The Effects of Short-Term Changes in Sodium Intake on Plasma Marinobufagenin Levels in Patients with Primary Salt-Sensitive and Salt-Insensitive Hypertension
by: Katarzyna Łabno-Kirszniok, et al.
Published: (2021-04-01)

Na<sup>+</sup>, K<sup>+</sup>-ATPase α Isoforms and Endogenous Cardiac Steroids in Prefrontal Cortex of Bipolar Patients and Controls
by: Shiv Vardan Singh, et al.
Published: (2020-08-01)

Marinobufagenin, Left Ventricular Hypertrophy and Residual Renal Function in Kidney Transplant Recipients
by: Davide Bolignano, et al.
Published: (2023-04-01)

New Insights on the Role of Marinobufagenin from Bench to Bedside in Cardiovascular and Kidney Diseases
by: Nazareno Carullo, et al.
Published: (2023-07-01)

Na+/K+-ATPase regulates the K+/Na+ homeostasis in the intertidal macroalgae, Neoporphyra haitanensis, in response to salt stress
by: Qi Chen, et al.
Published: (2023-01-01)

The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT Study
by: Michél Strauss-Kruger, et al.
Published: (2020-10-01)

Unveiling the Role of Cholesterol in Subnanomolar Ouabain Rescue of Cortical Neurons from Calcium Overload Caused by Excitotoxic Insults
by: Dmitry A. Sibarov, et al.
Published: (2023-08-01)

Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis
by: Sławomira Drzymała-Czyż, et al.
Published: (2021-02-01)

Stable potassium isotopes (41K/39K) track transcellular and paracellular potassium transport in biological systems
by: John A. Higgins, et al.
Published: (2022-10-01)

Cardiotonic Steroids—A Possible Link Between High-Salt Diet and Organ Damage
by: Aneta Paczula, et al.
Published: (2019-01-01)

Evaluation of Na+, K+-ATPase activity in the brain of young rats after acute administration of fenproporex
by: Gislaine T. Rezin, et al.
Published: (2014-05-01)

Sodium pumps in the Malpighian tubule of Rhodnius sp.
by: CARUSO-NEVES CELSO, et al.
Published: (2000-01-01)

Cellular Pathophysiology of Leptospirosis: Role of Na/K-ATPase
by: Cassiano Felippe Gonçalves-de-Albuquerque, et al.
Published: (2023-06-01)

At the double for tumor suppressor
by: Mahendra Sonawane
Published: (2016-07-01)

The modulation of erythrocyte Na+/K+-ATPase activity by curcumin
by: Prabhakar Singh, et al.
Published: (2015-11-01)

Effect of GRK4 on renal gastrin receptor regulation in hypertension
by: Xuewei Xia, et al.
Published: (2023-12-01)

Astrocytes—The Ultimate Effectors of Long-Range Neuromodulatory Networks?
by: Anthony G. Pacholko, et al.
Published: (2020-09-01)

Interaction Interface of Aβ<sub>42</sub> with Human Na,K-ATPase Studied by MD and ITC and Inhibitor Screening by MD
by: Alexei A. Adzhubei, et al.
Published: (2022-07-01)

Effect of Ouabain on Glutamate Transport in the Hippocampus of Rats with LPS-Induced Neuroinflammation
by: Israel José Pereira Garcia, et al.
Published: (2023-03-01)

High-Intensity Training Represses FXYD5 and Glycosylates Na,K-ATPase in Type II Muscle Fibres, Which Are Linked with Improved Muscle K<sup>+</sup> Handling and Performance
by: Morten Hostrup, et al.
Published: (2023-03-01)

Kinetic contribution to extracellular Na+/K+ selectivity in the Na+/K+ pump
by: Elizabeth Vleeskens, et al.
Published: (2018-05-01)

Isoquinolone alkaloids mitigate microscopic digestive tract lesions induced by sub-acute ruminal acidosis (SARA) in feedlot cattle
by: Adrien Wilhelm Dilger Sanches, et al.
Published: (2020-06-01)

Endogenous Digitalis-like Factors: An Overview of the History
by: Vardaman eBuckalew
Published: (2015-04-01)

Effects of high-salinity on the expression of aquaporins and ion transport-related genes in Chinese shrimp (Fenneropenaeus chinensis)
by: Zhitong Deng, et al.
Published: (2023-06-01)

Mechanisms of Sodium Transport in Plants—Progresses and Challenges
by: Monika Keisham, et al.
Published: (2018-02-01)

Analysis of Phytosterols Content in Italian-Standard Espresso Coffee
by: Franks Kamgang Nzekoue, et al.
Published: (2021-08-01)

Mechanisms of Na+ uptake from freshwater habitats in animals
by: Carol Eunmi Lee, et al.
Published: (2022-10-01)

Long-term Intracerebroventricular Administration of Ouabain Causes Motor Impairments in C57Bl/6 Mice
by: Yulia A. Timoshina, et al.
Published: (2023-12-01)

Antioxidant Therapy Reduces Oxidative Stress, Restores Na,K-ATPase Function and Induces Neuroprotection in Rodent Models of Seizure and Epilepsy: A Systematic Review and Meta-Analysis
by: Anderson Dutra de Melo, et al.
Published: (2023-07-01)

Erythrocyte Deformability and Na,K-ATPase Activity in Various Pathophysiological Situations and Their Protection by Selected Nutritional Antioxidants in Humans
by: Jana Radosinska, et al.
Published: (2021-11-01)

Insulin reverses impaired alveolar fluid clearance in ARDS by inhibiting LPS-induced autophagy and inflammatory
by: Xu-peng Wen, et al.
Published: (2023-08-01)

Maternal magnesium sulfate administration increases early-onset hyperkalemia risk in premature infants: A propensity score-matched, case-control study
by: Sayu Omori-Shimano, et al.
Published: (2023-03-01)

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit
by: Julia Hatzold, et al.
Published: (2016-05-01)

Effect of ouabain on calcium signaling in rodent brain: A systematic review of in vitro studies
by: Jacqueline Alves Leite, et al.
Published: (2022-08-01)

The effect of salinity on osmoregulation and development of the juvenile fat snook, Centropomus parallelus (POEY)
by: FC. Sterzelecki, et al.