Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia)
Avian influenza virus (AIV) in Asia is a complex system with numerous subtypes and a highly porous wild birds-poultry interface. Certain AIV subtypes, such as H14, are underrepresented in current surveillance efforts, leaving gaps in our understanding of their ecology and evolution. The detection of...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
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Taylor & Francis Group
2024-12-01
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| Colección: | Emerging Microbes and Infections |
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| Acceso en línea: | https://www.tandfonline.com/doi/10.1080/22221751.2023.2297552 |
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| author | Jurre Y. Siegers Michelle Wille Sokhoun Yann Songha Tok Sarath Sin Sokha Chea Alice Porco Sreyem Sours Vutha Chim Samban Chea Kimtuo Chhel Sothyra Tum San Sorn Makara Hak Peter Thielen Vijaykrishna Dhanasekaran Erik A. Karlsson |
| author_facet | Jurre Y. Siegers Michelle Wille Sokhoun Yann Songha Tok Sarath Sin Sokha Chea Alice Porco Sreyem Sours Vutha Chim Samban Chea Kimtuo Chhel Sothyra Tum San Sorn Makara Hak Peter Thielen Vijaykrishna Dhanasekaran Erik A. Karlsson |
| author_sort | Jurre Y. Siegers |
| collection | DOAJ |
| description | Avian influenza virus (AIV) in Asia is a complex system with numerous subtypes and a highly porous wild birds-poultry interface. Certain AIV subtypes, such as H14, are underrepresented in current surveillance efforts, leaving gaps in our understanding of their ecology and evolution. The detection of rare subtype H14 in domestic ducks in Southeast Asia comprises a geographic region and domestic bird population previously unassociated with this subtype. These H14 viruses have a complex evolutionary history involving gene reassortment events. They share sequence similarity to AIVs endemic in Cambodian ducks, and Eurasian low pathogenicity and high pathogenicity H5Nx AIVs. The detection of these H14 viruses in Southeast Asian domestic poultry further advances our knowledge of the ecology and evolution of this subtype and reinforces the need for continued, longitudinal, active surveillance in domestic and wild birds. Additionally, in vivo and in vitro risk assessment should encompass rare AIV subtypes, as they have the potential to establish in poultry systems. |
| first_indexed | 2024-04-24T07:59:51Z |
| format | Article |
| id | doaj.art-d901b16498394eb998a3cd7be74ca1f5 |
| institution | Directory Open Access Journal |
| issn | 2222-1751 |
| language | English |
| last_indexed | 2025-02-17T21:28:14Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj.art-d901b16498394eb998a3cd7be74ca1f52024-12-07T04:40:16ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512024-12-0113110.1080/22221751.2023.2297552Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia)Jurre Y. Siegers0Michelle Wille1Sokhoun Yann2Songha Tok3Sarath Sin4Sokha Chea5Alice Porco6Sreyem Sours7Vutha Chim8Samban Chea9Kimtuo Chhel10Sothyra Tum11San Sorn12Makara Hak13Peter Thielen14Vijaykrishna Dhanasekaran15Erik A. Karlsson16Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaCentre for Pathogen Genomics, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, AustraliaVirology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaVirology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaVirology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaWildlife Conservation Society, Phnom Penh, CambodiaWildlife Conservation Society, Phnom Penh, CambodiaWildlife Conservation Society, Phnom Penh, CambodiaNational Animal Health and Production Research Institute, Phnom Penh, CambodiaVirology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaVirology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaNational Animal Health and Production Research Institute, Phnom Penh, CambodiaNational Animal Health and Production Research Institute, Phnom Penh, CambodiaFood and Agriculture Organization of the United Nations Country Office, Phnom Penh, CambodiaJohns Hopkins University Applied Physics Laboratory, Laurel, MD, USASchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, People’s Republic of ChinaVirology Unit, Institute Pasteur du Cambodge, Phnom Penh, CambodiaAvian influenza virus (AIV) in Asia is a complex system with numerous subtypes and a highly porous wild birds-poultry interface. Certain AIV subtypes, such as H14, are underrepresented in current surveillance efforts, leaving gaps in our understanding of their ecology and evolution. The detection of rare subtype H14 in domestic ducks in Southeast Asia comprises a geographic region and domestic bird population previously unassociated with this subtype. These H14 viruses have a complex evolutionary history involving gene reassortment events. They share sequence similarity to AIVs endemic in Cambodian ducks, and Eurasian low pathogenicity and high pathogenicity H5Nx AIVs. The detection of these H14 viruses in Southeast Asian domestic poultry further advances our knowledge of the ecology and evolution of this subtype and reinforces the need for continued, longitudinal, active surveillance in domestic and wild birds. Additionally, in vivo and in vitro risk assessment should encompass rare AIV subtypes, as they have the potential to establish in poultry systems.https://www.tandfonline.com/doi/10.1080/22221751.2023.2297552H14N2surveillanceavian influenzaphylogeneticsSoutheast Asia |
| spellingShingle | Jurre Y. Siegers Michelle Wille Sokhoun Yann Songha Tok Sarath Sin Sokha Chea Alice Porco Sreyem Sours Vutha Chim Samban Chea Kimtuo Chhel Sothyra Tum San Sorn Makara Hak Peter Thielen Vijaykrishna Dhanasekaran Erik A. Karlsson Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia) Emerging Microbes and Infections H14N2 surveillance avian influenza phylogenetics Southeast Asia |
| title | Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia) |
| title_full | Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia) |
| title_fullStr | Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia) |
| title_full_unstemmed | Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia) |
| title_short | Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia) |
| title_sort | detection and phylogenetic analysis of contemporary h14n2 avian influenza a virus in domestic ducks in southeast asia cambodia |
| topic | H14N2 surveillance avian influenza phylogenetics Southeast Asia |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2023.2297552 |
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