Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A<sub>1</sub> and A<sub>3</sub> Adenosine Receptors

Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A<sub>1</sub> and A<sub>3</sub> Adenosine Receptors

Adenosine receptors (ARs) are being explored to generate non-opioid pain therapeutics. Vanilloid compounds, curcumin, capsaicin, and vanillin possess antinociceptive properties through their interactions with the transient receptor potential channel family. However, their binding with adenosine rece...

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Bibliographic Details
Main Authors: Luke J. Hamilton, Mahesh Pattabiraman, Haizhen A. Zhong, Michaela Walker, Hilary Vaughn, Surabhi Chandra
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceuticals
Subjects:
adenosine receptors
curcumin
vanilloid compounds
pain
photochemistry
A<sub>1</sub>AR
Online Access:https://www.mdpi.com/1424-8247/16/7/917

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