SARS-CoV-2 Quasispecies Provides an Advantage Mutation Pool for the Epidemic Variants

SARS-CoV-2 Quasispecies Provides an Advantage Mutation Pool for the Epidemic Variants

ABSTRACT The dynamics of quasispecies afford RNA viruses a great fitness on cell tropism and host range. To study the quasispecies features and the intra-host evolution of SARS-CoV-2, we collected nine confirmed patients and sequenced the haplotypes of spike gene using a single-molecule real-time pl...

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Bibliographic Details
Main Authors: Fengming Sun, Xiuhua Wang, Shun Tan, Yunjie Dan, Yanqiu Lu, Juan Zhang, Junli Xu, Zhaoxia Tan, Xiaomei Xiang, Yi Zhou, Weiwei He, Xing Wan, Wei Zhang, Yaokai Chen, Wenting Tan, Guohong Deng
Format: Article
Language:English
Published: American Society for Microbiology 2021-09-01
Series:Microbiology Spectrum
Subjects:
quasispecies
SARS-CoV-2
COVID-19
spike gene
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00261-21

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