The Korean Hypertension Cohort study: design and baseline characteristics
Background/Aims Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients. Methods The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiova...
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| Format: | Article |
| Language: | English |
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The Korean Association of Internal Medicine
2021-09-01
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| Series: | The Korean Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://www.kjim.org/upload/pdf/kjim-2020-551.pdf |
| _version_ | 1819023644603449344 |
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| author | Hae-Young Lee Ju-Yeon Lee Ho-Gyun Shin Song-Hee Cho Kyun-Ik Park Gyu-Chul Oh Seung-Pyo Lee Hogon Kim Hee-Sun Lee Kwang-Il Kim Si-Hyuck Kang Jang Hoon Lee Se Yong Jang Ju-Hee Lee Kye Hun Kim Jae Yeong Cho Jae-Hyeong Park Jieun Jang Sue K. Park Jean Kyung Bak |
| author_facet | Hae-Young Lee Ju-Yeon Lee Ho-Gyun Shin Song-Hee Cho Kyun-Ik Park Gyu-Chul Oh Seung-Pyo Lee Hogon Kim Hee-Sun Lee Kwang-Il Kim Si-Hyuck Kang Jang Hoon Lee Se Yong Jang Ju-Hee Lee Kye Hun Kim Jae Yeong Cho Jae-Hyeong Park Jieun Jang Sue K. Park Jean Kyung Bak |
| author_sort | Hae-Young Lee |
| collection | DOAJ |
| description | Background/Aims Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients. Methods The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hypertensive patients, who were presenting for the first time and were diagnosed with HT as a main disease from 2006 to 2011. Long-term survival data over a period of approximately 9 years were obtained from the national health insurance claim and national health examination data. Results This cohort enrolled 11,083 patients with HT. The mean age was 58.87 ± 11.5 years, 50.5% were male, and 31.4% were never-treated HT. Of the enrolled patients, 32.9% and 37.7% belonged to the high and moderate cardiovascular risk groups, respectively. Initial blood pressures were 149.4 ± 18.5/88.5 ± 12.5 mmHg. During the 2 years hospital data follow-up period, blood pressures lowered to 130.8 ± 14.1/78.0 ± 9.7 mmHg with 1.9 ± 1.0 tablet doses of antihypertensive medication. Cardiovascular events occurred in 7.5% of the overall patients; 8.5%, 8.8%, and 4.7% in the high, moderate, and low risk patients, respectively. Conclusions The KHC study has provided important information on the long-term outcomes of HT patients according to the blood pressure, comorbid diseases, medication, and adherence, as well as health behaviors and health resource use. |
| first_indexed | 2024-12-21T04:42:10Z |
| format | Article |
| id | doaj.art-d904c368382e4e7a983ca87a90ea66b2 |
| institution | Directory Open Access Journal |
| issn | 1226-3303 2005-6648 |
| language | English |
| last_indexed | 2024-12-21T04:42:10Z |
| publishDate | 2021-09-01 |
| publisher | The Korean Association of Internal Medicine |
| record_format | Article |
| series | The Korean Journal of Internal Medicine |
| spelling | doaj.art-d904c368382e4e7a983ca87a90ea66b22022-12-21T19:15:40ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482021-09-013651115112510.3904/kjim.2020.551170523The Korean Hypertension Cohort study: design and baseline characteristicsHae-Young Lee0Ju-Yeon Lee1Ho-Gyun Shin2Song-Hee Cho3Kyun-Ik Park4Gyu-Chul Oh5Seung-Pyo Lee6Hogon Kim7Hee-Sun Lee8Kwang-Il Kim9Si-Hyuck Kang10Jang Hoon Lee11Se Yong Jang12Ju-Hee Lee13Kye Hun Kim14Jae Yeong Cho15Jae-Hyeong Park16Jieun Jang17Sue K. Park18Jean Kyung Bak19 Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea College of Pharmacy, Seoul National University, Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Department of Internal Medicine, Seoul National University Bundang Hospital, Sungnam, Korea Department of Internal Medicine, Seoul National University Bundang Hospital, Sungnam, Korea Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea Department of Cardiovascular Medicine, Chonnam National University Hospital, Gwangju, Korea Department of Cardiovascular Medicine, Chonnam National University Hospital, Gwangju, Korea Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, KoreaBackground/Aims Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients. Methods The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hypertensive patients, who were presenting for the first time and were diagnosed with HT as a main disease from 2006 to 2011. Long-term survival data over a period of approximately 9 years were obtained from the national health insurance claim and national health examination data. Results This cohort enrolled 11,083 patients with HT. The mean age was 58.87 ± 11.5 years, 50.5% were male, and 31.4% were never-treated HT. Of the enrolled patients, 32.9% and 37.7% belonged to the high and moderate cardiovascular risk groups, respectively. Initial blood pressures were 149.4 ± 18.5/88.5 ± 12.5 mmHg. During the 2 years hospital data follow-up period, blood pressures lowered to 130.8 ± 14.1/78.0 ± 9.7 mmHg with 1.9 ± 1.0 tablet doses of antihypertensive medication. Cardiovascular events occurred in 7.5% of the overall patients; 8.5%, 8.8%, and 4.7% in the high, moderate, and low risk patients, respectively. Conclusions The KHC study has provided important information on the long-term outcomes of HT patients according to the blood pressure, comorbid diseases, medication, and adherence, as well as health behaviors and health resource use.http://www.kjim.org/upload/pdf/kjim-2020-551.pdfhypertensioncohort |
| spellingShingle | Hae-Young Lee Ju-Yeon Lee Ho-Gyun Shin Song-Hee Cho Kyun-Ik Park Gyu-Chul Oh Seung-Pyo Lee Hogon Kim Hee-Sun Lee Kwang-Il Kim Si-Hyuck Kang Jang Hoon Lee Se Yong Jang Ju-Hee Lee Kye Hun Kim Jae Yeong Cho Jae-Hyeong Park Jieun Jang Sue K. Park Jean Kyung Bak The Korean Hypertension Cohort study: design and baseline characteristics The Korean Journal of Internal Medicine hypertension cohort |
| title | The Korean Hypertension Cohort study: design and baseline characteristics |
| title_full | The Korean Hypertension Cohort study: design and baseline characteristics |
| title_fullStr | The Korean Hypertension Cohort study: design and baseline characteristics |
| title_full_unstemmed | The Korean Hypertension Cohort study: design and baseline characteristics |
| title_short | The Korean Hypertension Cohort study: design and baseline characteristics |
| title_sort | korean hypertension cohort study design and baseline characteristics |
| topic | hypertension cohort |
| url | http://www.kjim.org/upload/pdf/kjim-2020-551.pdf |
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