Manganese-enhanced MRI to evaluate neurodegenerative changes in a rat model of kainic acid-induced excitotoxicity
PURPOSEManganese-enhanced magnetic resonance imaging (MEMRI) has been used to detect brain activity based on the ability of active neurons to take up manganese ions through calcium channels. Kainic acid (KA), an analog of excitotoxic glutamate, can elicit selective neuronal death in the brains of ro...
Main Authors: | Melda Apaydın, Vedat Evren, Oytun Erbaş, Cem Çallı, Gönül O. Peker, Dilek Taşkıran |
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Format: | Article |
Language: | English |
Published: |
Galenos Publishing House
2013-09-01
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Series: | Diagnostic and Interventional Radiology |
Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/manganese-enhanced-mr-to-evaluate-neurodegenerativ/56466
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