Structure of a heteropolymeric type 4 pilus from a monoderm bacterium

Abstract Type 4 pili (T4P) are important virulence factors, which belong to a superfamily of nanomachines ubiquitous in prokaryotes, called type 4 filaments (T4F). T4F are defined as helical polymers of type 4 pilins. Recent advances in cryo-electron microscopy (cryo-EM) led to structures of several...

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Bibliographic Details
Main Authors: Robin Anger, Laetitia Pieulle, Meriam Shahin, Odile Valette, Hugo Le Guenno, Artemis Kosta, Vladimir Pelicic, Rémi Fronzes
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42872-5