Application of proteomics technology in dry eye disease and acupuncture treatment
Dry eye disease(DED)refers to a condition characterized by reduced stability of the tear film or an imbalance in the microenvironment of the ocular surface, resulting from abnormalities in quality, quantity and kinetics of tear. This condition leads to various ocular discomforts and even visual impa...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2024-01-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2024/1/202401011.pdf |
| _version_ | 1797376315093942272 |
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| author | Wei Qingbo Ding Ning Yang Xiaocun Wu Xia Shen Huxing Gao Weiping Wu Yunchuan Jiang Zhixin |
| author_facet | Wei Qingbo Ding Ning Yang Xiaocun Wu Xia Shen Huxing Gao Weiping Wu Yunchuan Jiang Zhixin |
| author_sort | Wei Qingbo |
| collection | DOAJ |
| description | Dry eye disease(DED)refers to a condition characterized by reduced stability of the tear film or an imbalance in the microenvironment of the ocular surface, resulting from abnormalities in quality, quantity and kinetics of tear. This condition leads to various ocular discomforts and even visual impairment. The pathogenesis of DED is multifactorial and current treatment mainly focuses on symptom relief and preservation of visual function. Acupuncture has shown effectiveness in treating dry eye, although its underlying mechanism remains incompletely understood. Proteomics technology offers a comprehensive and systematic approach to studying the functions, structures and interactions of proteins. Its application in DED research can provide valuable insights into the dynamic changes in protein levels associated with different etiology or the course of DED and facilitate the identification of potential biomarkers. Furthermore, proteomics can systematically explore the regulatory mechanisms underlying acupuncture treatment for DED, providing a theoretical basis for acupuncture treatment research and contributing to the understanding of its effects at a fundamental level. This paper aims to explore the potential application of proteomics in both clinical and basic research on DED. Ultimately, it strives to offer scientific and effective strategies for the diagnosis and treatment of DED and advance our knowledge of the mechanisms underlying acupuncture therapy. |
| first_indexed | 2024-03-08T19:36:46Z |
| format | Article |
| id | doaj.art-d91548dcbdd54176a7e5dc5d937a5f87 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-03-08T19:36:46Z |
| publishDate | 2024-01-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-d91548dcbdd54176a7e5dc5d937a5f872023-12-26T02:07:29ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232024-01-01241586110.3980/j.issn.1672-5123.2024.1.11202401011Application of proteomics technology in dry eye disease and acupuncture treatmentWei Qingbo0Ding Ning1Yang Xiaocun2Wu Xia3Shen Huxing4Gao Weiping5Wu Yunchuan6Jiang Zhixin7Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, ChinaNanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, ChinaNanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, ChinaNanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, ChinaDepartmnt of Ophthalmology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, ChinaDepartmnt of Ophthalmology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, ChinaNanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, ChinaJiangsu Health Development Research Center, Nanjing 210003, Jiangsu Province, ChinaDry eye disease(DED)refers to a condition characterized by reduced stability of the tear film or an imbalance in the microenvironment of the ocular surface, resulting from abnormalities in quality, quantity and kinetics of tear. This condition leads to various ocular discomforts and even visual impairment. The pathogenesis of DED is multifactorial and current treatment mainly focuses on symptom relief and preservation of visual function. Acupuncture has shown effectiveness in treating dry eye, although its underlying mechanism remains incompletely understood. Proteomics technology offers a comprehensive and systematic approach to studying the functions, structures and interactions of proteins. Its application in DED research can provide valuable insights into the dynamic changes in protein levels associated with different etiology or the course of DED and facilitate the identification of potential biomarkers. Furthermore, proteomics can systematically explore the regulatory mechanisms underlying acupuncture treatment for DED, providing a theoretical basis for acupuncture treatment research and contributing to the understanding of its effects at a fundamental level. This paper aims to explore the potential application of proteomics in both clinical and basic research on DED. Ultimately, it strives to offer scientific and effective strategies for the diagnosis and treatment of DED and advance our knowledge of the mechanisms underlying acupuncture therapy.http://ies.ijo.cn/cn_publish/2024/1/202401011.pdfdry eye diseaseacupunctureproteomics |
| spellingShingle | Wei Qingbo Ding Ning Yang Xiaocun Wu Xia Shen Huxing Gao Weiping Wu Yunchuan Jiang Zhixin Application of proteomics technology in dry eye disease and acupuncture treatment Guoji Yanke Zazhi dry eye disease acupuncture proteomics |
| title | Application of proteomics technology in dry eye disease and acupuncture treatment |
| title_full | Application of proteomics technology in dry eye disease and acupuncture treatment |
| title_fullStr | Application of proteomics technology in dry eye disease and acupuncture treatment |
| title_full_unstemmed | Application of proteomics technology in dry eye disease and acupuncture treatment |
| title_short | Application of proteomics technology in dry eye disease and acupuncture treatment |
| title_sort | application of proteomics technology in dry eye disease and acupuncture treatment |
| topic | dry eye disease acupuncture proteomics |
| url | http://ies.ijo.cn/cn_publish/2024/1/202401011.pdf |
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