3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41

Abstract 3-(4-hydroxy-3-methoxyphenyl) propionic acid (HMPA) is a metabolite produced by the gut microbiota through the conversion of 4-hydroxy-3-methoxycinnamic acid (HMCA), which is a widely distributed hydroxycinnamic acid-derived metabolite found abundantly in plants. Several beneficial effects...

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Bibliographic Details
Main Authors: Ryuji Ohue-Kitano, Yuki Masujima, Shota Nishikawa, Masayo Iwasa, Yosuke Nishitani, Hideaki Kawakami, Hiroshige Kuwahara, Ikuo Kimura
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48525-3

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