Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer
Triple-negative breast cancer (TNBC) accounts for approximately 15%–20% of all breast cancers. Patients with TNBC have a rapidly progressive clinical course, an earlier age of onset, faster distant recurrence, and more common visceral metastases as compared with other subtypes. However, treatment of...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
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Magazine House of Cancer Research on Prevention and Treatment
2023-07-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1426 |
| _version_ | 1827861138195349504 |
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| author | SHI Chao ZHANG Xiangmei LIU Yunjiang |
| author_facet | SHI Chao ZHANG Xiangmei LIU Yunjiang |
| author_sort | SHI Chao |
| collection | DOAJ |
| description | Triple-negative breast cancer (TNBC) accounts for approximately 15%–20% of all breast cancers. Patients with TNBC have a rapidly progressive clinical course, an earlier age of onset, faster distant recurrence, and more common visceral metastases as compared with other subtypes. However, treatment of TNBC is often limited to chemotherapy and has a poor prognosis. Therefore, developing the best treatment strategy for patients is essential to reduce the burden of disease caused by TNBC. Various potential available drug targets have been discovered, as well as precision treatment and classified treatment are changing the clinical practice of TNBC, thereby indicating a new therapeutic area for TNBC in addition to traditional chemotherapy. This article reviews the systemic treatment options for TNBC in recent years, including immunotherapy and targeted therapy. |
| first_indexed | 2024-03-12T13:32:48Z |
| format | Article |
| id | doaj.art-d91bef16cd334020bec9ae505fec3f33 |
| institution | Directory Open Access Journal |
| issn | 1000-8578 |
| language | zho |
| last_indexed | 2024-03-12T13:32:48Z |
| publishDate | 2023-07-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj.art-d91bef16cd334020bec9ae505fec3f332023-08-24T06:55:31ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782023-07-0150771071610.3971/j.issn.1000-8578.2023.22.14268578.2023.22.1426Research Progress on Immunization and Targeted Therapy for Triple-negative Breast CancerSHI Chao0ZHANG Xiangmei1LIU Yunjiang2Breast Center, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, ChinaBreast Center, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, ChinaBreast Center, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, ChinaTriple-negative breast cancer (TNBC) accounts for approximately 15%–20% of all breast cancers. Patients with TNBC have a rapidly progressive clinical course, an earlier age of onset, faster distant recurrence, and more common visceral metastases as compared with other subtypes. However, treatment of TNBC is often limited to chemotherapy and has a poor prognosis. Therefore, developing the best treatment strategy for patients is essential to reduce the burden of disease caused by TNBC. Various potential available drug targets have been discovered, as well as precision treatment and classified treatment are changing the clinical practice of TNBC, thereby indicating a new therapeutic area for TNBC in addition to traditional chemotherapy. This article reviews the systemic treatment options for TNBC in recent years, including immunotherapy and targeted therapy.http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1426triple-negative breast cancerimmunotherapytargeted therapylag3 |
| spellingShingle | SHI Chao ZHANG Xiangmei LIU Yunjiang Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer Zhongliu Fangzhi Yanjiu triple-negative breast cancer immunotherapy targeted therapy lag3 |
| title | Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer |
| title_full | Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer |
| title_fullStr | Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer |
| title_full_unstemmed | Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer |
| title_short | Research Progress on Immunization and Targeted Therapy for Triple-negative Breast Cancer |
| title_sort | research progress on immunization and targeted therapy for triple negative breast cancer |
| topic | triple-negative breast cancer immunotherapy targeted therapy lag3 |
| url | http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1426 |
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