Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings

Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings

To reduce the dosage size of amorphous solid dispersion (ASD)-based formulations, it is of interest to devise formulation strategies that allow increased drug loading (DL) without compromising dissolution performance. The aim of this study was to explore how surfactant addition impacts drug release...

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Bibliographic Details
Main Authors: Sugandha Saboo, Pradnya Bapat, Dana E. Moseson, Umesh S. Kestur, Lynne S. Taylor
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
amorphous solid dispersions
drug release
polymer release
congruent
surfactant
drug loading
Online Access:https://www.mdpi.com/1999-4923/13/5/735

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