Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis
Background and purpose: Tuberculosis (TB) is an infectious disease that is lethal in many cases. The aim of this study was to evaluate the clinical and laboratory findings in patients hospitalized with tuberculosis. Materials and methods: A cross-sectional study was carried out in 61 patients with t...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2017-09-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-9695-en.html |
| _version_ | 1797943742033821696 |
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| author | Farhang Babamahmoodi Roya Ghasemian Jamshid Yazdani Charati Elham Afzalian ashkezari Leila Delavarian |
| author_facet | Farhang Babamahmoodi Roya Ghasemian Jamshid Yazdani Charati Elham Afzalian ashkezari Leila Delavarian |
| author_sort | Farhang Babamahmoodi |
| collection | DOAJ |
| description | Background and purpose: Tuberculosis (TB) is an infectious disease that is lethal in many cases. The aim of this study was to evaluate the clinical and laboratory findings in patients hospitalized with tuberculosis.
Materials and methods: A cross-sectional study was carried out in 61 patients with tuberculosis in Razi Qaemshahr Hospital , Iran 2014-2015. We compared paraclinical and clinical findings in patients, those who died, individuals with recurrent TB, and patients with underlying diseases. Data was analyzed in SPSS V19. All P values less than 0.5 were considered significant.
Results: Significant differences were seen in ALP, RBC count, and hemoglobin in patients who had relapsed serum and new cases. Also, there were significant differences between alive and dead patients in levels of ALT, ALP, PPD, FBS, and creatinine levels. The HCT level, FBS, RBC, MCHC, platelet count, and serum ferritin differed significantly in patients who were HIV-positive and negative. Moreover, we found significant differences in MCV, WBC, MCH, MCHC, and AST between TB patients with and without liver disease. In TB patients with and without diabetes the levels of ALT and BS were significantly different.
Conclusion: Comparison of paraclinical outcomes in TB patients with and without underlying diseases, proves the importance of early diagnosis of clinical disorders in these patients. Therefore, elimination of these causes can lead to faster recovery and better treatment response in these patients. |
| first_indexed | 2024-04-10T20:28:59Z |
| format | Article |
| id | doaj.art-d921629a72444561a164fc08a797cf63 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:28:59Z |
| publishDate | 2017-09-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-d921629a72444561a164fc08a797cf632023-01-25T07:52:00ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792017-09-01271527287Comprehensive Study of Clinical and Laboratory Findings in Patients with TuberculosisFarhang Babamahmoodi0Roya Ghasemian1Jamshid Yazdani Charati2Elham Afzalian ashkezari3Leila Delavarian4 Professor, Department of Infectious Diseases, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Infectious Diseases, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Biostatistics, Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran Resident in Infectious Diseases, Student Research Committee, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran BSc in Nursing, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Tuberculosis (TB) is an infectious disease that is lethal in many cases. The aim of this study was to evaluate the clinical and laboratory findings in patients hospitalized with tuberculosis. Materials and methods: A cross-sectional study was carried out in 61 patients with tuberculosis in Razi Qaemshahr Hospital , Iran 2014-2015. We compared paraclinical and clinical findings in patients, those who died, individuals with recurrent TB, and patients with underlying diseases. Data was analyzed in SPSS V19. All P values less than 0.5 were considered significant. Results: Significant differences were seen in ALP, RBC count, and hemoglobin in patients who had relapsed serum and new cases. Also, there were significant differences between alive and dead patients in levels of ALT, ALP, PPD, FBS, and creatinine levels. The HCT level, FBS, RBC, MCHC, platelet count, and serum ferritin differed significantly in patients who were HIV-positive and negative. Moreover, we found significant differences in MCV, WBC, MCH, MCHC, and AST between TB patients with and without liver disease. In TB patients with and without diabetes the levels of ALT and BS were significantly different. Conclusion: Comparison of paraclinical outcomes in TB patients with and without underlying diseases, proves the importance of early diagnosis of clinical disorders in these patients. Therefore, elimination of these causes can lead to faster recovery and better treatment response in these patients.http://jmums.mazums.ac.ir/article-1-9695-en.htmltuberculosisparaclinical findingspulmonary tuberculosisunderlying disease |
| spellingShingle | Farhang Babamahmoodi Roya Ghasemian Jamshid Yazdani Charati Elham Afzalian ashkezari Leila Delavarian Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis Journal of Mazandaran University of Medical Sciences tuberculosis paraclinical findings pulmonary tuberculosis underlying disease |
| title | Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis |
| title_full | Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis |
| title_fullStr | Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis |
| title_full_unstemmed | Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis |
| title_short | Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis |
| title_sort | comprehensive study of clinical and laboratory findings in patients with tuberculosis |
| topic | tuberculosis paraclinical findings pulmonary tuberculosis underlying disease |
| url | http://jmums.mazums.ac.ir/article-1-9695-en.html |
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