Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study.
BACKGROUND:Cocaine consumption can induce transient psychotic symptoms, which has been correlated with more severe addiction and aggressive behavior. However, little is known about the nature of the relationship between personality traits and psychotic symptoms in cocaine-dependent patients. This st...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4177812?pdf=render |
| _version_ | 1818251860528594944 |
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| author | Carlos Roncero Constanza Daigre Carmen Barral Elena Ros-Cucurull Lara Grau-López Laia Rodríguez-Cintas Nuria Tarifa Miguel Casas Sergi Valero |
| author_facet | Carlos Roncero Constanza Daigre Carmen Barral Elena Ros-Cucurull Lara Grau-López Laia Rodríguez-Cintas Nuria Tarifa Miguel Casas Sergi Valero |
| author_sort | Carlos Roncero |
| collection | DOAJ |
| description | BACKGROUND:Cocaine consumption can induce transient psychotic symptoms, which has been correlated with more severe addiction and aggressive behavior. However, little is known about the nature of the relationship between personality traits and psychotic symptoms in cocaine-dependent patients. This study examined the relationship between neuroticism and cocaine-induced psychosis. METHODS:A total of 231 cocaine-dependent patients seeking treatment were recruited to the study. Personality was evaluated by the Zuckerman-Kuhlman Personality Questionnaire. Cocaine-induced psychosis questionnaire, SCID-I, and SCID-II were used to evaluate comorbidity and clinical characteristics. Data analysis was performed in three steps: descriptive, bivariate, and multivariate analyses. RESULTS:Cocaine-induced psychosis was reported in 65.4% of the patients and some personality disorder in 46.8%. Two personality dimensions (Neuroticism-Anxiety and Aggression-Hostility) presented a significant effect on the risk of experiencing psychotic symptoms (t(229) = 2.69, p = 0.008; t(229) = 2.06, p = 0.004), and patients with psychotic symptoms showed higher scores in both variables. On the multivariate analysis, only Neuroticism remained as a significant personality factor independently associated with psychotic symptoms (Wald = 7.44, p<0.05, OR = 1.08, CI 95% 1.02-1.16) after controlling for age, gender and number of consumption substances. CONCLUSIONS:An association between high neuroticism scores and presence of psychotic symptoms induced by cocaine has been found, independently of other consumption variables. Personality dimensions should be evaluated in cocaine-dependent patients in order to detect high scores of neuroticism and warn patients about the risk of developing cocaine-induced psychotic symptoms. |
| first_indexed | 2024-12-12T16:15:00Z |
| format | Article |
| id | doaj.art-d922324bb9ec4e7da3ca323ce99a3597 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T16:15:00Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d922324bb9ec4e7da3ca323ce99a35972022-12-22T00:19:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0199e10611110.1371/journal.pone.0106111Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study.Carlos RonceroConstanza DaigreCarmen BarralElena Ros-CucurullLara Grau-LópezLaia Rodríguez-CintasNuria TarifaMiguel CasasSergi ValeroBACKGROUND:Cocaine consumption can induce transient psychotic symptoms, which has been correlated with more severe addiction and aggressive behavior. However, little is known about the nature of the relationship between personality traits and psychotic symptoms in cocaine-dependent patients. This study examined the relationship between neuroticism and cocaine-induced psychosis. METHODS:A total of 231 cocaine-dependent patients seeking treatment were recruited to the study. Personality was evaluated by the Zuckerman-Kuhlman Personality Questionnaire. Cocaine-induced psychosis questionnaire, SCID-I, and SCID-II were used to evaluate comorbidity and clinical characteristics. Data analysis was performed in three steps: descriptive, bivariate, and multivariate analyses. RESULTS:Cocaine-induced psychosis was reported in 65.4% of the patients and some personality disorder in 46.8%. Two personality dimensions (Neuroticism-Anxiety and Aggression-Hostility) presented a significant effect on the risk of experiencing psychotic symptoms (t(229) = 2.69, p = 0.008; t(229) = 2.06, p = 0.004), and patients with psychotic symptoms showed higher scores in both variables. On the multivariate analysis, only Neuroticism remained as a significant personality factor independently associated with psychotic symptoms (Wald = 7.44, p<0.05, OR = 1.08, CI 95% 1.02-1.16) after controlling for age, gender and number of consumption substances. CONCLUSIONS:An association between high neuroticism scores and presence of psychotic symptoms induced by cocaine has been found, independently of other consumption variables. Personality dimensions should be evaluated in cocaine-dependent patients in order to detect high scores of neuroticism and warn patients about the risk of developing cocaine-induced psychotic symptoms.http://europepmc.org/articles/PMC4177812?pdf=render |
| spellingShingle | Carlos Roncero Constanza Daigre Carmen Barral Elena Ros-Cucurull Lara Grau-López Laia Rodríguez-Cintas Nuria Tarifa Miguel Casas Sergi Valero Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study. PLoS ONE |
| title | Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study. |
| title_full | Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study. |
| title_fullStr | Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study. |
| title_full_unstemmed | Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study. |
| title_short | Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study. |
| title_sort | neuroticism associated with cocaine induced psychosis in cocaine dependent patients a cross sectional observational study |
| url | http://europepmc.org/articles/PMC4177812?pdf=render |
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