Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in <i>STAT2</i> KO Syrian Hamsters

Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in <i>STAT2</i> KO Syrian Hamsters

Zika virus (ZIKV) infection can cause severe congenital diseases, such as microcephaly, ocular defects and arthrogryposis in fetuses, and Guillain&#8315;Barr&#233; syndrome in adults. Efficacious therapeutic treatments for infected patients, as well as prophylactic treatments to prevent new...

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Bibliographic Details
Main Authors: Venkatraman Siddharthan, Jinxin Miao, Arnaud J Van Wettere, Rong Li, Hua Wu, Eddie Sullivan, Jinan Jiao, Jay W. Hooper, David Safronetz, John D. Morrey, Justin G. Julander, Zhongde Wang
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Viruses
Subjects:
<i>STAT2</i> KO hamster
transchromosomal bovine antibody
Zika virus
therapeutic
testis
Online Access:https://www.mdpi.com/1999-4915/11/2/92

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