Single-cell RNA sequencing analysis of human chondrocytes reveals cell–cell communication alterations mediated by interactive signaling pathways in osteoarthritis

Single-cell RNA sequencing analysis of human chondrocytes reveals cell–cell communication alterations mediated by interactive signaling pathways in osteoarthritis

Objective: Osteoarthritis (OA) is a common joint disorder characterized by degenerative articular cartilage, subchondral bone remodeling, and inflammation. Increasing evidence suggests that the substantial crosstalk between cartilage and synovium is closely related to Osteoarthritis development, but...

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Bibliographic Details
Main Authors: Xin Kang, Kailiang Zhang, Yakang Wang, Yang Zhao, Yao Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteoarthritis
cell-cell communication
single-cell transcriptomic sequencing
signaling pathway
chondrocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1099287/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1099287/full

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