Acute conditions in dermatology: toxic reactions and their treatment
Acute severe conditions caused by the use of various drugs are of particular difficulty in dermatological practice. Toxicodermic reactions include DRESS syndrome, StevensJohnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis and erythroderma of various origins. Thes...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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ZAO "Consilium Medicum"
2021-08-01
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| Series: | Consilium Medicum |
| Subjects: | |
| Online Access: | https://consilium.orscience.ru/2075-1753/article/viewFile/97105/71535 |
| _version_ | 1798025185161379840 |
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| author | Luiza R. Sakaniya Kristina T. Plieva Elena V. Denisova Irina M. Korsunskaya |
| author_facet | Luiza R. Sakaniya Kristina T. Plieva Elena V. Denisova Irina M. Korsunskaya |
| author_sort | Luiza R. Sakaniya |
| collection | DOAJ |
| description | Acute severe conditions caused by the use of various drugs are of particular difficulty in dermatological practice. Toxicodermic reactions include DRESS syndrome, StevensJohnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis and erythroderma of various origins. These disorders are characterized not only by skin lesions, but also toxic reactions in internal organs, which if untreated properly can be life-threatening. The first choice drugs for such reactions are systemic glucocorticosteroids, in particular betamethasone derivatives. Our own experience and numerous studies confirm the effectiveness of such drugs. However, it should be remembered that uncontrolled or prolonged use of systemic glucocorticosteroids can aggravate the patient's condition and lead to unwanted adverse reactions. |
| first_indexed | 2024-04-11T18:14:40Z |
| format | Article |
| id | doaj.art-d92a743cb84e4d299f3abb3e1c01652d |
| institution | Directory Open Access Journal |
| issn | 2075-1753 2542-2170 |
| language | Russian |
| last_indexed | 2024-04-11T18:14:40Z |
| publishDate | 2021-08-01 |
| publisher | ZAO "Consilium Medicum" |
| record_format | Article |
| series | Consilium Medicum |
| spelling | doaj.art-d92a743cb84e4d299f3abb3e1c01652d2022-12-22T04:09:59ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702021-08-0123866867110.26442/20751753.2021.8.2011804500Acute conditions in dermatology: toxic reactions and their treatmentLuiza R. Sakaniya0https://orcid.org/0000-0003-2027-5987Kristina T. Plieva1https://orcid.org/0000-0001-9351-1034Elena V. Denisova2https://orcid.org/0000-0002-4887-284XIrina M. Korsunskaya3https://orcid.org/0000-0002-6583-0318Center for Theoretical Problems of Physicochemical PharmacologyMoscow Scientific and Practical Center of Dermatology, Venereology and CosmetologyCenter for Theoretical Problems of Physicochemical PharmacologyCenter for Theoretical Problems of Physicochemical PharmacologyAcute severe conditions caused by the use of various drugs are of particular difficulty in dermatological practice. Toxicodermic reactions include DRESS syndrome, StevensJohnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis and erythroderma of various origins. These disorders are characterized not only by skin lesions, but also toxic reactions in internal organs, which if untreated properly can be life-threatening. The first choice drugs for such reactions are systemic glucocorticosteroids, in particular betamethasone derivatives. Our own experience and numerous studies confirm the effectiveness of such drugs. However, it should be remembered that uncontrolled or prolonged use of systemic glucocorticosteroids can aggravate the patient's condition and lead to unwanted adverse reactions.https://consilium.orscience.ru/2075-1753/article/viewFile/97105/71535toxidermiaerythrodermadrug reactionssystemic glucocorticosteroidsbetamethasone |
| spellingShingle | Luiza R. Sakaniya Kristina T. Plieva Elena V. Denisova Irina M. Korsunskaya Acute conditions in dermatology: toxic reactions and their treatment Consilium Medicum toxidermia erythroderma drug reactions systemic glucocorticosteroids betamethasone |
| title | Acute conditions in dermatology: toxic reactions and their treatment |
| title_full | Acute conditions in dermatology: toxic reactions and their treatment |
| title_fullStr | Acute conditions in dermatology: toxic reactions and their treatment |
| title_full_unstemmed | Acute conditions in dermatology: toxic reactions and their treatment |
| title_short | Acute conditions in dermatology: toxic reactions and their treatment |
| title_sort | acute conditions in dermatology toxic reactions and their treatment |
| topic | toxidermia erythroderma drug reactions systemic glucocorticosteroids betamethasone |
| url | https://consilium.orscience.ru/2075-1753/article/viewFile/97105/71535 |
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