Dynamical Analysis of a Fractional Order HIV/AIDS Model

This article discusses a dynamical analysis of the fractional-order model of HIV/AIDS. Biologically, the rate of subpopulation growth also depends on all previous conditions/memory effects. The dependency of the growth of subpopulations on the past conditions is considered by applying fractional der...

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Main Authors: Septiangga Van Nyek Perdana Putra, Agus Suryanto, Nur Shofianah
Format: Article
Language:English
Published: Universitas Muhammadiyah Mataram 2021-04-01
Series:JTAM (Jurnal Teori dan Aplikasi Matematika)
Subjects:
Online Access:http://journal.ummat.ac.id/index.php/jtam/article/view/3224
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author Septiangga Van Nyek Perdana Putra
Agus Suryanto
Nur Shofianah
author_facet Septiangga Van Nyek Perdana Putra
Agus Suryanto
Nur Shofianah
author_sort Septiangga Van Nyek Perdana Putra
collection DOAJ
description This article discusses a dynamical analysis of the fractional-order model of HIV/AIDS. Biologically, the rate of subpopulation growth also depends on all previous conditions/memory effects. The dependency of the growth of subpopulations on the past conditions is considered by applying fractional derivatives. The model is assumed to consist of susceptible, HIV infected, HIV infected with treatment, resistance, and AIDS. The fractional-order model of HIV/AIDS with Caputo fractional-order derivative operators is constructed and then, the dynamical analysis is performed to determine the equilibrium points, local stability and global stability of the equilibrium points. The dynamical analysis results show that the model has two equilibrium points, namely the disease-free equilibrium point and endemic equilibrium point. The disease-free equilibrium point always exists and is globally asymptotically stable when the basic reproduction number is less than one. The endemic equilibrium point exists if the basic reproduction number is more than one and is globally asymptotically stable unconditionally. To illustrate the dynamical analysis, we perform some numerical simulation using the Predictor-Corrector method. Numerical simulation results support the analytical results.
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spelling doaj.art-d92d2290e6da414085913a8c7014c25f2022-12-21T19:58:53ZengUniversitas Muhammadiyah MataramJTAM (Jurnal Teori dan Aplikasi Matematika)2597-75122614-11752021-04-0151142710.31764/jtam.v5i1.32242462Dynamical Analysis of a Fractional Order HIV/AIDS ModelSeptiangga Van Nyek Perdana Putra0Agus Suryanto1Nur Shofianah2Brawijaya UniversityBrawijaya UniversityBrawijaya UniversityThis article discusses a dynamical analysis of the fractional-order model of HIV/AIDS. Biologically, the rate of subpopulation growth also depends on all previous conditions/memory effects. The dependency of the growth of subpopulations on the past conditions is considered by applying fractional derivatives. The model is assumed to consist of susceptible, HIV infected, HIV infected with treatment, resistance, and AIDS. The fractional-order model of HIV/AIDS with Caputo fractional-order derivative operators is constructed and then, the dynamical analysis is performed to determine the equilibrium points, local stability and global stability of the equilibrium points. The dynamical analysis results show that the model has two equilibrium points, namely the disease-free equilibrium point and endemic equilibrium point. The disease-free equilibrium point always exists and is globally asymptotically stable when the basic reproduction number is less than one. The endemic equilibrium point exists if the basic reproduction number is more than one and is globally asymptotically stable unconditionally. To illustrate the dynamical analysis, we perform some numerical simulation using the Predictor-Corrector method. Numerical simulation results support the analytical results.http://journal.ummat.ac.id/index.php/jtam/article/view/3224fractional-orderpece methodhiv/aidsepidemic model
spellingShingle Septiangga Van Nyek Perdana Putra
Agus Suryanto
Nur Shofianah
Dynamical Analysis of a Fractional Order HIV/AIDS Model
JTAM (Jurnal Teori dan Aplikasi Matematika)
fractional-order
pece method
hiv/aids
epidemic model
title Dynamical Analysis of a Fractional Order HIV/AIDS Model
title_full Dynamical Analysis of a Fractional Order HIV/AIDS Model
title_fullStr Dynamical Analysis of a Fractional Order HIV/AIDS Model
title_full_unstemmed Dynamical Analysis of a Fractional Order HIV/AIDS Model
title_short Dynamical Analysis of a Fractional Order HIV/AIDS Model
title_sort dynamical analysis of a fractional order hiv aids model
topic fractional-order
pece method
hiv/aids
epidemic model
url http://journal.ummat.ac.id/index.php/jtam/article/view/3224
work_keys_str_mv AT septianggavannyekperdanaputra dynamicalanalysisofafractionalorderhivaidsmodel
AT agussuryanto dynamicalanalysisofafractionalorderhivaidsmodel
AT nurshofianah dynamicalanalysisofafractionalorderhivaidsmodel