Hypoxia Pathway Proteins are Master Regulators of Erythropoiesis

Hypoxia Pathway Proteins are Master Regulators of Erythropoiesis

Erythropoiesis is a complex process driving the production of red blood cells. During homeostasis, adult erythropoiesis takes place in the bone marrow and is tightly controlled by erythropoietin (EPO), a central hormone mainly produced in renal EPO-producing cells. The expression of EPO is strictly...

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Bibliographic Details
Main Authors: Deepika Watts, Diana Gaete, Diego Rodriguez, David Hoogewijs, Martina Rauner, Sundary Sormendi, Ben Wielockx
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxia
erythropoiesis
EPO
HIF
CKD
Online Access:https://www.mdpi.com/1422-0067/21/21/8131

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