Neuroimaging characteristics of mitochondrial disease in children
Mitochondrial disease (MD) in children most often involve the central nervous system. CT, MRI and magnetic resonance spectroscopy (MRS) often show basal ganglia lesions, white matter encephalopathy, stroke⁃like changes, cerebellum or brain atrophy, calcification, lactic acid (Lac) peak and other cha...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2022-12-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2611 |
| _version_ | 1797960150777069568 |
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| author | QIU Yin⁃feng GUO Yi |
| author_facet | QIU Yin⁃feng GUO Yi |
| author_sort | QIU Yin⁃feng |
| collection | DOAJ |
| description | Mitochondrial disease (MD) in children most often involve the central nervous system. CT, MRI and magnetic resonance spectroscopy (MRS) often show basal ganglia lesions, white matter encephalopathy, stroke⁃like changes, cerebellum or brain atrophy, calcification, lactic acid (Lac) peak and other characteristic imaging changes. Some clinically rare mitochondrial syndrome also have typical neuroimaging changes, which have important implications for the diagnosis and antidiastole of diseases and understanding of the pathophysiological mechanism of central nervous system involvement. In this study, common neuroimaging changes of MD and the neuroimaging characteristics of some mitochondrial syndrome were described to help the early diagnosis and treatment of MD from the perspective of neuroimaging. |
| first_indexed | 2024-04-11T00:40:49Z |
| format | Article |
| id | doaj.art-d92d6891aac6444ab2a6f13a0a02979b |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-04-11T00:40:49Z |
| publishDate | 2022-12-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-d92d6891aac6444ab2a6f13a0a02979b2023-01-06T06:14:08ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312022-12-0112121094109810.3969/j.issn.1672⁃6731.2022.12.015Neuroimaging characteristics of mitochondrial disease in childrenQIU Yin⁃feng0GUO Yi1Department of Neurology, Children's Hospital of Chongqing Medical UniversityDepartment of Neurology, Children's Hospital of Chongqing Medical UniversityMitochondrial disease (MD) in children most often involve the central nervous system. CT, MRI and magnetic resonance spectroscopy (MRS) often show basal ganglia lesions, white matter encephalopathy, stroke⁃like changes, cerebellum or brain atrophy, calcification, lactic acid (Lac) peak and other characteristic imaging changes. Some clinically rare mitochondrial syndrome also have typical neuroimaging changes, which have important implications for the diagnosis and antidiastole of diseases and understanding of the pathophysiological mechanism of central nervous system involvement. In this study, common neuroimaging changes of MD and the neuroimaging characteristics of some mitochondrial syndrome were described to help the early diagnosis and treatment of MD from the perspective of neuroimaging.http://www.cjcnn.org/index.php/cjcnn/article/view/2611mitochondrial diseasesmagnetic resonance imagingchildreview |
| spellingShingle | QIU Yin⁃feng GUO Yi Neuroimaging characteristics of mitochondrial disease in children Chinese Journal of Contemporary Neurology and Neurosurgery mitochondrial diseases magnetic resonance imaging child review |
| title | Neuroimaging characteristics of mitochondrial disease in children |
| title_full | Neuroimaging characteristics of mitochondrial disease in children |
| title_fullStr | Neuroimaging characteristics of mitochondrial disease in children |
| title_full_unstemmed | Neuroimaging characteristics of mitochondrial disease in children |
| title_short | Neuroimaging characteristics of mitochondrial disease in children |
| title_sort | neuroimaging characteristics of mitochondrial disease in children |
| topic | mitochondrial diseases magnetic resonance imaging child review |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/2611 |
| work_keys_str_mv | AT qiuyinfeng neuroimagingcharacteristicsofmitochondrialdiseaseinchildren AT guoyi neuroimagingcharacteristicsofmitochondrialdiseaseinchildren |