Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study
Gait analysis is clinically relevant in persons with multiple sclerosis (PwMS) and consists of several joint angular displacement–time relationships and spatiotemporal parameters. However, it lacks representation by means of diagrams in which knee-angle/hip-angle and knee-angle/ankle-angle variation...
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MDPI AG
2022-07-01
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| Online Access: | https://www.mdpi.com/2076-3417/12/14/7223 |
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| author | Riccardo Di Giminiani Davide Di Lorenzo Stefano La Greca Luca Russo Francesco Masedu Rocco Totaro Elvira Padua |
| author_facet | Riccardo Di Giminiani Davide Di Lorenzo Stefano La Greca Luca Russo Francesco Masedu Rocco Totaro Elvira Padua |
| author_sort | Riccardo Di Giminiani |
| collection | DOAJ |
| description | Gait analysis is clinically relevant in persons with multiple sclerosis (PwMS) and consists of several joint angular displacement–time relationships and spatiotemporal parameters. However, it lacks representation by means of diagrams in which knee-angle/hip-angle and knee-angle/ankle-angle variations are plotted against each other at the same points of time. Three-dimensional kinematic analysis was performed on 20 subjects (10 PwMS/10 healthy controls, HCs), and the knee-angle/hip-angle and knee-angle/ankle-angle diagrams of both lower limbs were determined in the sagittal plane while walking on a motorized treadmill. The area (a quantifier of range of motion) and the perimeter (a quantifier of coordination) of angle-angle diagram loops were calculated. PwMS showed reduced knee-angle/ankle-angle loops compared to HCs (<i>p</i> < 0.05), whereas the hip-angle/ankle-angle loops between the PwMS and HCs was not significant (<i>p</i> > 0.05). Similarly, the activation of leg muscles showed significant differences between PwMS and HCs (<i>p</i> ranged from 0.05 to 0.001). The results indicate that the proposed knee-angle/hip-angle diagram is feasible and could be applied as a reliable tool in future studies aimed at assessing the acute and long-term effects of specific exercise programmes and/or pharmacological treatment in PwMS. |
| first_indexed | 2024-03-09T03:43:52Z |
| format | Article |
| id | doaj.art-d92d9742908243cab96ce161ddf49355 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T03:43:52Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-d92d9742908243cab96ce161ddf493552023-12-03T14:37:13ZengMDPI AGApplied Sciences2076-34172022-07-011214722310.3390/app12147223Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary StudyRiccardo Di Giminiani0Davide Di Lorenzo1Stefano La Greca2Luca Russo3Francesco Masedu4Rocco Totaro5Elvira Padua6Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Human Sciences, Italian University Line—IUL, 50122 Florance, ItalyDepartment of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, ItalyCentre for the Diagnosis and Treatment of Demyelinating Diseases, Hospital of L’Aquila-Sulmona-Avezzano, 67100 L’Aquila, ItalyDepartment of Human Science and Promotion of Quality of Life, San Raffaele Open University, 00166 Rome, ItalyGait analysis is clinically relevant in persons with multiple sclerosis (PwMS) and consists of several joint angular displacement–time relationships and spatiotemporal parameters. However, it lacks representation by means of diagrams in which knee-angle/hip-angle and knee-angle/ankle-angle variations are plotted against each other at the same points of time. Three-dimensional kinematic analysis was performed on 20 subjects (10 PwMS/10 healthy controls, HCs), and the knee-angle/hip-angle and knee-angle/ankle-angle diagrams of both lower limbs were determined in the sagittal plane while walking on a motorized treadmill. The area (a quantifier of range of motion) and the perimeter (a quantifier of coordination) of angle-angle diagram loops were calculated. PwMS showed reduced knee-angle/ankle-angle loops compared to HCs (<i>p</i> < 0.05), whereas the hip-angle/ankle-angle loops between the PwMS and HCs was not significant (<i>p</i> > 0.05). Similarly, the activation of leg muscles showed significant differences between PwMS and HCs (<i>p</i> ranged from 0.05 to 0.001). The results indicate that the proposed knee-angle/hip-angle diagram is feasible and could be applied as a reliable tool in future studies aimed at assessing the acute and long-term effects of specific exercise programmes and/or pharmacological treatment in PwMS.https://www.mdpi.com/2076-3417/12/14/7223gait analysiswalkinghip-angle/knee-angleknee-angle/ankle angleEMG activityneurodegenerative disease |
| spellingShingle | Riccardo Di Giminiani Davide Di Lorenzo Stefano La Greca Luca Russo Francesco Masedu Rocco Totaro Elvira Padua Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study Applied Sciences gait analysis walking hip-angle/knee-angle knee-angle/ankle angle EMG activity neurodegenerative disease |
| title | Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study |
| title_full | Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study |
| title_fullStr | Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study |
| title_full_unstemmed | Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study |
| title_short | Angle-Angle Diagrams in the Assessment of Locomotion in Persons with Multiple Sclerosis: A Preliminary Study |
| title_sort | angle angle diagrams in the assessment of locomotion in persons with multiple sclerosis a preliminary study |
| topic | gait analysis walking hip-angle/knee-angle knee-angle/ankle angle EMG activity neurodegenerative disease |
| url | https://www.mdpi.com/2076-3417/12/14/7223 |
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