Role of Fibroblast Growth Factor-23 in Innate Immune Responses

Role of Fibroblast Growth Factor-23 in Innate Immune Responses

Fibroblast growth factor-23 (FGF-23) is a bone-derived hormone that activates FGFR/α-Klotho binary complexes in the kidney renal tubules to regulate phosphate reabsorption and vitamin D metabolism. The objective of this review is to discuss the emerging data that show that FGF-23 has functions beyon...

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Bibliographic Details
Main Authors: Elizabeth A. Fitzpatrick, Xiaobin Han, Zhousheng Xiao, L. Darryl Quarles
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Endocrinology
Subjects:
fibroblast growth factor-23
innate immunity
klotho
macrophage activation
PMNs
LPS stimulation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00320/full

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