Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1)

Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1)

Stress-inducible phosphoprotein I (STIP1, STI1 or HOP) is a co-chaperone intermediating Hsp70/Hsp90 exchange of client proteins, but it can also be secreted to trigger prion protein-mediated neuronal signaling. Some mothers of children with autism spectrum disorders (ASD) present antibodies against...

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Bibliographic Details
Main Authors: Flavio H. Beraldo, Anu Thomas, Benjamin Kolisnyk, Pedro H. Hirata, Xavier De Jaeger, Amanda C. Martyn, Jue Fan, Daniela F. Goncalves, Matthew F. Cowan, Talal Masood, Vilma R. Martins, Robert Gros, Vania F. Prado, Marco A. M. Prado
Format: Article
Language:English
Published: The Company of Biologists 2015-11-01
Series:Disease Models & Mechanisms
Subjects:
Touchscreen
Autism
ASD
Stress-inducible phosphoprotein 1
Attention deficits
Mouse model
BAC
Online Access:http://dmm.biologists.org/content/8/11/1457

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