Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
Woody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recover...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/11/2689 |
| Summary: | Woody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO<sub>2</sub>) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. <i>chinensis</i> SC-CO<sub>2</sub> extracts. |
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| ISSN: | 1420-3049 |