Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
Woody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recover...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/11/2689 |
| _version_ | 1797565678006304768 |
|---|---|
| author | Mayya Razgonova Alexander Zakharenko Konstantin Pikula Ekaterina Kim Valery Chernyshev Sezai Ercisli Giancarlo Cravotto Kirill Golokhvast |
| author_facet | Mayya Razgonova Alexander Zakharenko Konstantin Pikula Ekaterina Kim Valery Chernyshev Sezai Ercisli Giancarlo Cravotto Kirill Golokhvast |
| author_sort | Mayya Razgonova |
| collection | DOAJ |
| description | Woody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO<sub>2</sub>) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. <i>chinensis</i> SC-CO<sub>2</sub> extracts. |
| first_indexed | 2024-03-10T19:16:24Z |
| format | Article |
| id | doaj.art-d932cf14fbb34b94b829526acc4a43f6 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T19:16:24Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-d932cf14fbb34b94b829526acc4a43f62023-11-20T03:23:31ZengMDPI AGMolecules1420-30492020-06-012511268910.3390/molecules25112689Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MSMayya Razgonova0Alexander Zakharenko1Konstantin Pikula2Ekaterina Kim3Valery Chernyshev4Sezai Ercisli5Giancarlo Cravotto6Kirill Golokhvast7REC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaAgricultural Faculty, Department of Horticulture, Ataturk University, Erzurum 25240, TurkeyDipartimento di Scienza e Technologia del Farmaco, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaWoody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO<sub>2</sub>) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. <i>chinensis</i> SC-CO<sub>2</sub> extracts.https://www.mdpi.com/1420-3049/25/11/2689<i>Schisandra chinensis</i>supercritical fluid extractionHPLC-SPD-ESI-MS/MSlignans |
| spellingShingle | Mayya Razgonova Alexander Zakharenko Konstantin Pikula Ekaterina Kim Valery Chernyshev Sezai Ercisli Giancarlo Cravotto Kirill Golokhvast Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS Molecules <i>Schisandra chinensis</i> supercritical fluid extraction HPLC-SPD-ESI-MS/MS lignans |
| title | Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS |
| title_full | Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS |
| title_fullStr | Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS |
| title_full_unstemmed | Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS |
| title_short | Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS |
| title_sort | rapid mass spectrometric study of a supercritical co sub 2 sub extract from woody liana i schisandra chinensis i by hplc spd esi ms ms |
| topic | <i>Schisandra chinensis</i> supercritical fluid extraction HPLC-SPD-ESI-MS/MS lignans |
| url | https://www.mdpi.com/1420-3049/25/11/2689 |
| work_keys_str_mv | AT mayyarazgonova rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT alexanderzakharenko rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT konstantinpikula rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT ekaterinakim rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT valerychernyshev rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT sezaiercisli rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT giancarlocravotto rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms AT kirillgolokhvast rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms |