Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia
Purpose: To report a case of peripheral ulcerative keratitis and necrotizing scleritis precipitated by trauma in a patient with mixed cryoglobulinemia due to hepatitis C viral infection. Methods: Case report and literature review. Results: A 62-year-old man with a history of mixed cryoglobulinemia d...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2011-12-01
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| Series: | Case Reports in Ophthalmology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/334496 |
| _version_ | 1811255436535398400 |
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| author | Cameron Campbell Johnson Derek Hunter Ohlstein |
| author_facet | Cameron Campbell Johnson Derek Hunter Ohlstein |
| author_sort | Cameron Campbell Johnson |
| collection | DOAJ |
| description | Purpose: To report a case of peripheral ulcerative keratitis and necrotizing scleritis precipitated by trauma in a patient with mixed cryoglobulinemia due to hepatitis C viral infection. Methods: Case report and literature review. Results: A 62-year-old man with a history of mixed cryoglobulinemia developed an episode of necrotizing scleritis and peripheral ulcerative keratitis one month after repair of a traumatic scleral defect with patch grafting. This episode resolved following treatment with high-dose corticosteroids and the patient underwent successful repeat patch grafting along with a free conjunctival autograft. This is the second reported case of necrotizing scleritis and peripheral ulcerative keratitis associated with mixed cryoglobulinemia. Conclusion: Ophthalmologists should be aware of the association between mixed cryoglobulinemia and necrotizing scleritis/peripheral ulcerative keratitis. Patients with this condition experiencing ocular trauma or undergoing ocular surgery should be monitored closely. |
| first_indexed | 2024-04-12T17:24:53Z |
| format | Article |
| id | doaj.art-d9370f100700497988b4b072e0c95aa2 |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-04-12T17:24:53Z |
| publishDate | 2011-12-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-d9370f100700497988b4b072e0c95aa22022-12-22T03:23:21ZengKarger PublishersCase Reports in Ophthalmology1663-26992011-12-012339239710.1159/000334496334496Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed CryoglobulinemiaCameron Campbell JohnsonDerek Hunter OhlsteinPurpose: To report a case of peripheral ulcerative keratitis and necrotizing scleritis precipitated by trauma in a patient with mixed cryoglobulinemia due to hepatitis C viral infection. Methods: Case report and literature review. Results: A 62-year-old man with a history of mixed cryoglobulinemia developed an episode of necrotizing scleritis and peripheral ulcerative keratitis one month after repair of a traumatic scleral defect with patch grafting. This episode resolved following treatment with high-dose corticosteroids and the patient underwent successful repeat patch grafting along with a free conjunctival autograft. This is the second reported case of necrotizing scleritis and peripheral ulcerative keratitis associated with mixed cryoglobulinemia. Conclusion: Ophthalmologists should be aware of the association between mixed cryoglobulinemia and necrotizing scleritis/peripheral ulcerative keratitis. Patients with this condition experiencing ocular trauma or undergoing ocular surgery should be monitored closely.http://www.karger.com/Article/FullText/334496ScleritisPeripheral ulcerative keratitisPUKMixed cryoglobulinemiaHepatitis C |
| spellingShingle | Cameron Campbell Johnson Derek Hunter Ohlstein Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia Case Reports in Ophthalmology Scleritis Peripheral ulcerative keratitis PUK Mixed cryoglobulinemia Hepatitis C |
| title | Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia |
| title_full | Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia |
| title_fullStr | Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia |
| title_full_unstemmed | Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia |
| title_short | Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia |
| title_sort | peripheral ulcerative keratitis and necrotizing scleritis initiated by trauma in the setting of mixed cryoglobulinemia |
| topic | Scleritis Peripheral ulcerative keratitis PUK Mixed cryoglobulinemia Hepatitis C |
| url | http://www.karger.com/Article/FullText/334496 |
| work_keys_str_mv | AT cameroncampbelljohnson peripheralulcerativekeratitisandnecrotizingscleritisinitiatedbytraumainthesettingofmixedcryoglobulinemia AT derekhunterohlstein peripheralulcerativekeratitisandnecrotizingscleritisinitiatedbytraumainthesettingofmixedcryoglobulinemia |