Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth
ObjectiveWe evaluated the effect on treatment using the new International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for gestational diabetes mellitus (GDM) diagnosis.MethodsSingleton pregnant women whose plasma glucose levels were ≥140 mg/dL on the 50 g glucose challenge te...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Obstetrics and Gynecology
2020-01-01
|
| Series: | Obstetrics & Gynecology Science |
| Subjects: | |
| Online Access: | http://ogscience.org/upload/pdf/ogs-63-19.pdf |
| _version_ | 1818188183790157824 |
|---|---|
| author | Kyoung-Hee Lee You-Jung Han Jin-Hoon Chung Moon-Young Kim Hyun-Mee Ryu Jin-Ha Kim Dong-Wook Kwak Sung-Hoon Kim Seongwoo Yang Minhyoung Kim |
| author_facet | Kyoung-Hee Lee You-Jung Han Jin-Hoon Chung Moon-Young Kim Hyun-Mee Ryu Jin-Ha Kim Dong-Wook Kwak Sung-Hoon Kim Seongwoo Yang Minhyoung Kim |
| author_sort | Kyoung-Hee Lee |
| collection | DOAJ |
| description | ObjectiveWe evaluated the effect on treatment using the new International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for gestational diabetes mellitus (GDM) diagnosis.MethodsSingleton pregnant women whose plasma glucose levels were ≥140 mg/dL on the 50 g glucose challenge test (GCT) underwent 75 g oral glucose tolerance for GDM diagnosis. During the first half of the study period, GDM was diagnosed using 2 abnormal values by Carpenter-Coustan (C-C) criteria. In the second half of the study period, 1 or more abnormal values by IADPSG criteria were used for GDM diagnosis. Pregnant women were classified into 5 groups: normal 50 g GCT, positive 50 g GCT but non-GDM, GDM by IADPSG criteria and non-treated, GDM by IADPSG criteria and treated, GDM by C-C criteria and treated. The odds ratios (ORs) for large for gestational age (LGA) and macrosomia were analyzed.ResultsOf the 2,678 patients, the frequency of GDM diagnosed by C-C and IADPSG criteria was 2.6% and 7.5%. ORs (95% confidence intervals [CIs]) for LGA and macrosomia in the group with GDM by IADPSG criteria and non-treated were 2.81 (95% CI, 1.47–5.38) and 2.84 (95% CI, 1.08–7.47). The risk of LGA and macrosomia did not increase in the group with GDM by IADPSG criteria and treated.ConclusionThe risk of LGA and macrosomia for mild GDM diagnosed solely by IADPSG criteria depends on whether they are treated or not. Treatment of GDM based on IADPSG criteria reduces the risk of excessive fetal growth.Trial RegistrationClinical Research Information Service Identifier: KCT0000776 |
| first_indexed | 2024-12-11T23:22:53Z |
| format | Article |
| id | doaj.art-d93898fc84a54a8b8dc620f65a6d156f |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-12-11T23:22:53Z |
| publishDate | 2020-01-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-d93898fc84a54a8b8dc620f65a6d156f2022-12-22T00:46:18ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802020-01-01631192610.5468/ogs.2020.63.1.19642Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growthKyoung-Hee Lee0You-Jung Han1Jin-Hoon Chung2Moon-Young Kim3Hyun-Mee Ryu4Jin-Ha Kim5Dong-Wook Kwak6Sung-Hoon Kim7Seongwoo Yang8Minhyoung Kim9Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, CHA Bundang Medical Center, CHA University, Seongnam, .KoreaDepartment of Obstetrics and Gynecology, Samsung Medical Center, Seoul, .KoreaDepartment of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, .KoreaDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, .KoreaDepartment of Internal Medicine, Institute of Health and Environment, Seoul National University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, MizMedi Hospital, Seoul, .KoreaObjectiveWe evaluated the effect on treatment using the new International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for gestational diabetes mellitus (GDM) diagnosis.MethodsSingleton pregnant women whose plasma glucose levels were ≥140 mg/dL on the 50 g glucose challenge test (GCT) underwent 75 g oral glucose tolerance for GDM diagnosis. During the first half of the study period, GDM was diagnosed using 2 abnormal values by Carpenter-Coustan (C-C) criteria. In the second half of the study period, 1 or more abnormal values by IADPSG criteria were used for GDM diagnosis. Pregnant women were classified into 5 groups: normal 50 g GCT, positive 50 g GCT but non-GDM, GDM by IADPSG criteria and non-treated, GDM by IADPSG criteria and treated, GDM by C-C criteria and treated. The odds ratios (ORs) for large for gestational age (LGA) and macrosomia were analyzed.ResultsOf the 2,678 patients, the frequency of GDM diagnosed by C-C and IADPSG criteria was 2.6% and 7.5%. ORs (95% confidence intervals [CIs]) for LGA and macrosomia in the group with GDM by IADPSG criteria and non-treated were 2.81 (95% CI, 1.47–5.38) and 2.84 (95% CI, 1.08–7.47). The risk of LGA and macrosomia did not increase in the group with GDM by IADPSG criteria and treated.ConclusionThe risk of LGA and macrosomia for mild GDM diagnosed solely by IADPSG criteria depends on whether they are treated or not. Treatment of GDM based on IADPSG criteria reduces the risk of excessive fetal growth.Trial RegistrationClinical Research Information Service Identifier: KCT0000776http://ogscience.org/upload/pdf/ogs-63-19.pdfgestational diabetescriteriatreatment |
| spellingShingle | Kyoung-Hee Lee You-Jung Han Jin-Hoon Chung Moon-Young Kim Hyun-Mee Ryu Jin-Ha Kim Dong-Wook Kwak Sung-Hoon Kim Seongwoo Yang Minhyoung Kim Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth Obstetrics & Gynecology Science gestational diabetes criteria treatment |
| title | Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth |
| title_full | Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth |
| title_fullStr | Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth |
| title_full_unstemmed | Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth |
| title_short | Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth |
| title_sort | treatment of gestational diabetes diagnosed by the iadpsg criteria decreases excessive fetal growth |
| topic | gestational diabetes criteria treatment |
| url | http://ogscience.org/upload/pdf/ogs-63-19.pdf |
| work_keys_str_mv | AT kyoungheelee treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT youjunghan treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT jinhoonchung treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT moonyoungkim treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT hyunmeeryu treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT jinhakim treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT dongwookkwak treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT sunghoonkim treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT seongwooyang treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth AT minhyoungkim treatmentofgestationaldiabetesdiagnosedbytheiadpsgcriteriadecreasesexcessivefetalgrowth |