Molecular Changes in Prader-Willi Syndrome Neurons Reveals Clues About Increased Autism Susceptibility

Molecular Changes in Prader-Willi Syndrome Neurons Reveals Clues About Increased Autism Susceptibility

Background: Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by hormonal dysregulation, obesity, intellectual disability, and behavioral problems. Most PWS cases are caused by paternal interstitial deletions of 15q11.2-q13.1, while a smaller number of cases are caused by ch...

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Bibliographic Details
Main Authors: A. Kaitlyn Victor, Martin Donaldson, Daniel Johnson, Winston Miller, Lawrence T. Reiter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
autism (ASD)
mitochondria
Prader-Willi syndrome (PWS)
neurodevelopment
dental pulp stem cell (DPSC)
mRNA seq
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.747855/full

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