Renal Endothelial Cytotoxicity Assay to Diagnose and Monitor Renal Transplant Recipients for Anti-Endothelial Antibodies

Renal Endothelial Cytotoxicity Assay to Diagnose and Monitor Renal Transplant Recipients for Anti-Endothelial Antibodies

Tissue-specific nonhuman leukocyte antigen (HLA) antigens can play crucial roles in allograft immunity and have been shown to trigger humoral responses leading to rejection of HLA-matched kidney allografts. Interest in the role of endothelial-specific antigens has grown over the past years, and seve...

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Bibliographic Details
Main Authors: Rosa G. M. Lammerts, Jacob van den Born, Magdalena Huberts-Kregel, Antonio W. Gomes-Neto, Mohammed R. Daha, Bouke G. Hepkema, Jan-Stephan Sanders, Robert A. Pol, Arjan Diepstra, Stefan P. Berger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
complement biology
crossmatch
cytotoxicity
desensitization
flow cytometry
non-HLA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.845187/full

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