Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways

Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways

Abstract Background In previous studies, we have shown that the combination of metformin and gefitinib inhibits the growth of bladder cancer cells. Here we examined whether the metformin analogue phenformin, either used alone or in combination with gefitinib, could inhibit growth of bladder cancer c...

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Bibliographic Details
Main Authors: Yanjun Huang, Sichun Zhou, Caimei He, Jun Deng, Ting Tao, Qiongli Su, Kwame Oteng Darko, Mei Peng, Xiaoping Yang
Format: Article
Language:English
Published: Wiley 2018-07-01
Series:Cancer Communications
Subjects:
Phenformin
Gefitinib
Bladder cancer
AMPK
EGFR
Online Access:http://link.springer.com/article/10.1186/s40880-018-0319-7

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