On-Chip Liquid Chromatography
On-chip liquid chromatography (LC) refers to LC technology that is miniaturized to fit on a microchip to enable fast, high-throughput analysis, with small sample volumes and low reagent consumption. Four different on-chip LC approaches have been developed to date: use of open-tubular, packed-particl...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Encyclopedia |
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| Online Access: | https://www.mdpi.com/2673-8392/2/1/41 |
| Summary: | On-chip liquid chromatography (LC) refers to LC technology that is miniaturized to fit on a microchip to enable fast, high-throughput analysis, with small sample volumes and low reagent consumption. Four different on-chip LC approaches have been developed to date: use of open-tubular, packed-particle, monolithic, and pillar array columns. These methods have been applied to proteomics as well as the analysis of small molecules and drugs in various biological samples. Recent advances in on-chip LC are summarized herein. |
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| ISSN: | 2673-8392 |