Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications
Abstract Offering high specificity and selectivity, molecularly imprinted polymers (MIPs) are synthetic polymeric affinity reagents that have become increasingly popular over the last couple of decades. Due to their long‐term chemical and physical stability and low production cost, they have become...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2023-07-01
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| Series: | Advanced Sensor Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/adsr.202200059 |
| _version_ | 1827896100338532352 |
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| author | Manlio Caldara Gil vanWissen Thomas J. Cleij Hanne Diliën Bart vanGrinsven Kasper Eersels Joseph W. Lowdon |
| author_facet | Manlio Caldara Gil vanWissen Thomas J. Cleij Hanne Diliën Bart vanGrinsven Kasper Eersels Joseph W. Lowdon |
| author_sort | Manlio Caldara |
| collection | DOAJ |
| description | Abstract Offering high specificity and selectivity, molecularly imprinted polymers (MIPs) are synthetic polymeric affinity reagents that have become increasingly popular over the last couple of decades. Due to their long‐term chemical and physical stability and low production cost, they have become an increasingly popular choice of receptor in the realm of sense. MIPs have therefore been associated with the detection of small molecules, proteins, cells, and pathogens, proving a highly robust and useful tool in the production of next‐gen sensing platforms. This said, the development of these sensors pivots on one simple fact; these receptors have to be deposited onto a substrate for their desired application. The deposition of MIPs during sensor fabrication is therefore of great importance, with the field utilizing an array of mechanical and chemical deposition methods to achieve this. To this end, this review, therefore, sets aim at coalescing these different deposition approaches, classifying them, and outlining their utility when it comes to receptor design and integration. Thus, offering a knowledge base on current deposition methods, potential future approaches and analyzing where the MIP deposition field is tending toward. |
| first_indexed | 2024-03-12T22:29:59Z |
| format | Article |
| id | doaj.art-d94ccc19f63a4d71af68b6ee7758ae01 |
| institution | Directory Open Access Journal |
| issn | 2751-1219 |
| language | English |
| last_indexed | 2024-03-12T22:29:59Z |
| publishDate | 2023-07-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced Sensor Research |
| spelling | doaj.art-d94ccc19f63a4d71af68b6ee7758ae012023-07-21T15:30:28ZengWiley-VCHAdvanced Sensor Research2751-12192023-07-0127n/an/a10.1002/adsr.202200059Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor ApplicationsManlio Caldara0Gil vanWissen1Thomas J. Cleij2Hanne Diliën3Bart vanGrinsven4Kasper Eersels5Joseph W. Lowdon6Sensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsSensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsSensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsSensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsSensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsSensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsSensor Engineering Department Faculty of Science and Engineering Maastricht University P.O. Box 616 Maastricht MD 6200 The NetherlandsAbstract Offering high specificity and selectivity, molecularly imprinted polymers (MIPs) are synthetic polymeric affinity reagents that have become increasingly popular over the last couple of decades. Due to their long‐term chemical and physical stability and low production cost, they have become an increasingly popular choice of receptor in the realm of sense. MIPs have therefore been associated with the detection of small molecules, proteins, cells, and pathogens, proving a highly robust and useful tool in the production of next‐gen sensing platforms. This said, the development of these sensors pivots on one simple fact; these receptors have to be deposited onto a substrate for their desired application. The deposition of MIPs during sensor fabrication is therefore of great importance, with the field utilizing an array of mechanical and chemical deposition methods to achieve this. To this end, this review, therefore, sets aim at coalescing these different deposition approaches, classifying them, and outlining their utility when it comes to receptor design and integration. Thus, offering a knowledge base on current deposition methods, potential future approaches and analyzing where the MIP deposition field is tending toward.https://doi.org/10.1002/adsr.202200059depositionmolecularly imprinted polymersread‐outreceptorssensing |
| spellingShingle | Manlio Caldara Gil vanWissen Thomas J. Cleij Hanne Diliën Bart vanGrinsven Kasper Eersels Joseph W. Lowdon Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications Advanced Sensor Research deposition molecularly imprinted polymers read‐out receptors sensing |
| title | Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications |
| title_full | Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications |
| title_fullStr | Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications |
| title_full_unstemmed | Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications |
| title_short | Deposition Methods for the Integration of Molecularly Imprinted Polymers (MIPs) in Sensor Applications |
| title_sort | deposition methods for the integration of molecularly imprinted polymers mips in sensor applications |
| topic | deposition molecularly imprinted polymers read‐out receptors sensing |
| url | https://doi.org/10.1002/adsr.202200059 |
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