Preparation of extemporaneous oral liquid in the hospital pharmacy
At the hospital, the pharmacist is constantly challenged to prepare extemporaneous solutions from tablets, capsules or drug powder for patients unable to swallow, such as pediatric, elderly and patients that use nasoenteric and nasogastric tubes. The preparation of extemporaneous solutions from caps...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade de São Paulo
2020-04-01
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| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100703&tlng=en |
| _version_ | 1811271377407180800 |
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| author | Márcio Robert Mattos da Silva Letícia Pereira Dysars Elisabete Pereira dos Santos Eduardo Ricci Júnior |
| author_facet | Márcio Robert Mattos da Silva Letícia Pereira Dysars Elisabete Pereira dos Santos Eduardo Ricci Júnior |
| author_sort | Márcio Robert Mattos da Silva |
| collection | DOAJ |
| description | At the hospital, the pharmacist is constantly challenged to prepare extemporaneous solutions from tablets, capsules or drug powder for patients unable to swallow, such as pediatric, elderly and patients that use nasoenteric and nasogastric tubes. The preparation of extemporaneous solutions from capsules, tablets and drug powder requires stability studies analysis. This article is a bibliographic review of preparation of extemporaneous oral liquid from solid oral dosage forms used in clinical practice. The selected articles contain all the information regarding manipulation techniques, pharmaceutical excipients, packaging, storage conditions and results of stability studies above 90% performed by HPLC analysis. In addition, a situational analysis of the strategies for the preparation of the extemporaneous solution was described to help the manipulator in the decision. The preparation of extemporaneous solution from solid oral dosage forms is based on information from official compendium or scientific literature, to ensure safe and effective manipulated medicine. |
| first_indexed | 2024-04-12T22:19:01Z |
| format | Article |
| id | doaj.art-d9558c14f7c448109aca3d62bcf6d110 |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-04-12T22:19:01Z |
| publishDate | 2020-04-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-d9558c14f7c448109aca3d62bcf6d1102022-12-22T03:14:26ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902020-04-015610.1590/s2175-97902019000418358Preparation of extemporaneous oral liquid in the hospital pharmacyMárcio Robert Mattos da SilvaLetícia Pereira DysarsElisabete Pereira dos SantosEduardo Ricci Júniorhttps://orcid.org/0000-0002-2550-696XAt the hospital, the pharmacist is constantly challenged to prepare extemporaneous solutions from tablets, capsules or drug powder for patients unable to swallow, such as pediatric, elderly and patients that use nasoenteric and nasogastric tubes. The preparation of extemporaneous solutions from capsules, tablets and drug powder requires stability studies analysis. This article is a bibliographic review of preparation of extemporaneous oral liquid from solid oral dosage forms used in clinical practice. The selected articles contain all the information regarding manipulation techniques, pharmaceutical excipients, packaging, storage conditions and results of stability studies above 90% performed by HPLC analysis. In addition, a situational analysis of the strategies for the preparation of the extemporaneous solution was described to help the manipulator in the decision. The preparation of extemporaneous solution from solid oral dosage forms is based on information from official compendium or scientific literature, to ensure safe and effective manipulated medicine.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100703&tlng=enExtemporaneous oral liquidStabilityHospital pharmacy |
| spellingShingle | Márcio Robert Mattos da Silva Letícia Pereira Dysars Elisabete Pereira dos Santos Eduardo Ricci Júnior Preparation of extemporaneous oral liquid in the hospital pharmacy Brazilian Journal of Pharmaceutical Sciences Extemporaneous oral liquid Stability Hospital pharmacy |
| title | Preparation of extemporaneous oral liquid in the hospital pharmacy |
| title_full | Preparation of extemporaneous oral liquid in the hospital pharmacy |
| title_fullStr | Preparation of extemporaneous oral liquid in the hospital pharmacy |
| title_full_unstemmed | Preparation of extemporaneous oral liquid in the hospital pharmacy |
| title_short | Preparation of extemporaneous oral liquid in the hospital pharmacy |
| title_sort | preparation of extemporaneous oral liquid in the hospital pharmacy |
| topic | Extemporaneous oral liquid Stability Hospital pharmacy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100703&tlng=en |
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