Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study

Objective To assess symptom presentation related to age, sex and previous medical history in patients with chest pain.Design Prospective observational cohort study.Setting Two-centre study in a Swedish county emergency medical service (EMS) organisation.Participants Unselected inclusion of 2917 pati...

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Main Authors: Johan Herlitz, Markus Lingman, Kristoffer Wibring, Angela Bång, Helena Pettersson, Anette Lerjebo
Format: Article
Language:English
Published: BMJ Publishing Group 2022-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/8/e054622.full
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author Johan Herlitz
Markus Lingman
Kristoffer Wibring
Angela Bång
Helena Pettersson
Anette Lerjebo
author_facet Johan Herlitz
Markus Lingman
Kristoffer Wibring
Angela Bång
Helena Pettersson
Anette Lerjebo
author_sort Johan Herlitz
collection DOAJ
description Objective To assess symptom presentation related to age, sex and previous medical history in patients with chest pain.Design Prospective observational cohort study.Setting Two-centre study in a Swedish county emergency medical service (EMS) organisation.Participants Unselected inclusion of 2917 patients with chest pain cared for by the EMS during 2018.Data analysis Multivariate analysis on the association between symptom characteristics, patients’ sex, age, previous acute coronary syndrome (ACS) or diabetes and the final outcome of acute myocardial infarction (AMI).Results Symptomology in patients assessed by the EMS due to acute chest pain varied with sex and age and also with previous ACS or diabetes. Women suffered more often from nausea (OR 1.6) and pain in throat (OR 2.1) or back (OR 2.1). Their pain was more often affected by palpation (1.7) or movement (OR 1.4). Older patients more often described pain onset while sleeping (OR 1.5) and that the onset of symptoms was slow, over hours rather than minutes (OR 1.4). They were less likely to report pain in other parts of their body than their chest (OR 1.4). They were to a lesser extent clammy (OR 0.6) or nauseous (OR 0.6). These differences were present regardless of whether the symptoms were caused by AMI or not.Conclusions A number of aspects of the symptom of chest pain appear to differ in unselected prehospital patients with chest pain in relation to age, sex and medical history, regardless of whether the chest pain was caused by a myocardial infarction or not. This complicates the possibility in prehospital care of using symptoms to predict the underlying aetiology of acute chest pain.
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spelling doaj.art-d955e19f77584672a1420545a9ba57252022-12-22T04:00:33ZengBMJ Publishing GroupBMJ Open2044-60552022-08-0112810.1136/bmjopen-2021-054622Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort studyJohan Herlitz0Markus Lingman1Kristoffer Wibring2Angela Bång3Helena Pettersson4Anette Lerjebo5Caring Science, Faculty of Caring Science, Borås, Sweden1Institute of Health and Care Sciences, University of Gothenburg, SE1Institute of Health and Care Sciences, University of Gothenburg, SE1Institute of Health and Care Sciences, University of Gothenburg, SEDepartment of Ambulance and Prehospital Care, Halland County, Halmstad, SwedenDepartment of Ambulance and Prehospital Care, Halland County, Halmstad, SwedenObjective To assess symptom presentation related to age, sex and previous medical history in patients with chest pain.Design Prospective observational cohort study.Setting Two-centre study in a Swedish county emergency medical service (EMS) organisation.Participants Unselected inclusion of 2917 patients with chest pain cared for by the EMS during 2018.Data analysis Multivariate analysis on the association between symptom characteristics, patients’ sex, age, previous acute coronary syndrome (ACS) or diabetes and the final outcome of acute myocardial infarction (AMI).Results Symptomology in patients assessed by the EMS due to acute chest pain varied with sex and age and also with previous ACS or diabetes. Women suffered more often from nausea (OR 1.6) and pain in throat (OR 2.1) or back (OR 2.1). Their pain was more often affected by palpation (1.7) or movement (OR 1.4). Older patients more often described pain onset while sleeping (OR 1.5) and that the onset of symptoms was slow, over hours rather than minutes (OR 1.4). They were less likely to report pain in other parts of their body than their chest (OR 1.4). They were to a lesser extent clammy (OR 0.6) or nauseous (OR 0.6). These differences were present regardless of whether the symptoms were caused by AMI or not.Conclusions A number of aspects of the symptom of chest pain appear to differ in unselected prehospital patients with chest pain in relation to age, sex and medical history, regardless of whether the chest pain was caused by a myocardial infarction or not. This complicates the possibility in prehospital care of using symptoms to predict the underlying aetiology of acute chest pain.https://bmjopen.bmj.com/content/12/8/e054622.full
spellingShingle Johan Herlitz
Markus Lingman
Kristoffer Wibring
Angela Bång
Helena Pettersson
Anette Lerjebo
Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study
BMJ Open
title Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study
title_full Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study
title_fullStr Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study
title_full_unstemmed Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study
title_short Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study
title_sort clinical presentation in ems patients with acute chest pain in relation to sex age and medical history prospective cohort study
url https://bmjopen.bmj.com/content/12/8/e054622.full
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