Immune thrombocytopenic purpura

Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count <150,000 u/L), which is not associated with a systemic illness. ITP is reported in approximately 2 per 100,000 adults. The mean age of diagnosis is 50 years. ITP is more common...

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Main Authors: Abir Zainal, Amr Salama, Richard Alweis
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2019-01-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://dx.doi.org/10.1080/20009666.2019.1565884
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author Abir Zainal
Amr Salama
Richard Alweis
author_facet Abir Zainal
Amr Salama
Richard Alweis
author_sort Abir Zainal
collection DOAJ
description Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count <150,000 u/L), which is not associated with a systemic illness. ITP is reported in approximately 2 per 100,000 adults. The mean age of diagnosis is 50 years. ITP is more common in females of childbearing age and in pregnancy. In adults, the course is more chronic although spontaneous remission can also occur within months of initial diagnosis. A thorough and timely workup of thrombocytopenia is imperative to rule out other differentials of ITP as it is considered a diagnosis of exclusion. Primary care physicians encounter patients who exhibit signs of thrombocytopenia such as petechiae or purpura on a regular basis. A high index of clinical suspicion is required to accurately diagnose ITP and commence the appropriate treatment including glucocorticoids to increase the chances of a favorable prognosis as described by the authors.
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spelling doaj.art-d958a6d6f7f347bd85d1b963b2a90a7b2023-01-02T23:06:30ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662019-01-0191596110.1080/20009666.2019.15658841565884Immune thrombocytopenic purpuraAbir Zainal0Amr Salama1Richard Alweis2Unity Hospital, Rochester Regional HealthUnity Hospital, Rochester Regional HealthUnity Hospital, Rochester Regional HealthImmune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count <150,000 u/L), which is not associated with a systemic illness. ITP is reported in approximately 2 per 100,000 adults. The mean age of diagnosis is 50 years. ITP is more common in females of childbearing age and in pregnancy. In adults, the course is more chronic although spontaneous remission can also occur within months of initial diagnosis. A thorough and timely workup of thrombocytopenia is imperative to rule out other differentials of ITP as it is considered a diagnosis of exclusion. Primary care physicians encounter patients who exhibit signs of thrombocytopenia such as petechiae or purpura on a regular basis. A high index of clinical suspicion is required to accurately diagnose ITP and commence the appropriate treatment including glucocorticoids to increase the chances of a favorable prognosis as described by the authors.http://dx.doi.org/10.1080/20009666.2019.1565884Immune thrombocytopenic purpurahematologyplateletscorticosteroids
spellingShingle Abir Zainal
Amr Salama
Richard Alweis
Immune thrombocytopenic purpura
Journal of Community Hospital Internal Medicine Perspectives
Immune thrombocytopenic purpura
hematology
platelets
corticosteroids
title Immune thrombocytopenic purpura
title_full Immune thrombocytopenic purpura
title_fullStr Immune thrombocytopenic purpura
title_full_unstemmed Immune thrombocytopenic purpura
title_short Immune thrombocytopenic purpura
title_sort immune thrombocytopenic purpura
topic Immune thrombocytopenic purpura
hematology
platelets
corticosteroids
url http://dx.doi.org/10.1080/20009666.2019.1565884
work_keys_str_mv AT abirzainal immunethrombocytopenicpurpura
AT amrsalama immunethrombocytopenicpurpura
AT richardalweis immunethrombocytopenicpurpura