Immune thrombocytopenic purpura
Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count <150,000 u/L), which is not associated with a systemic illness. ITP is reported in approximately 2 per 100,000 adults. The mean age of diagnosis is 50 years. ITP is more common...
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Format: | Article |
Language: | English |
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Greater Baltimore Medical Center
2019-01-01
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Series: | Journal of Community Hospital Internal Medicine Perspectives |
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Online Access: | http://dx.doi.org/10.1080/20009666.2019.1565884 |
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author | Abir Zainal Amr Salama Richard Alweis |
author_facet | Abir Zainal Amr Salama Richard Alweis |
author_sort | Abir Zainal |
collection | DOAJ |
description | Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count <150,000 u/L), which is not associated with a systemic illness. ITP is reported in approximately 2 per 100,000 adults. The mean age of diagnosis is 50 years. ITP is more common in females of childbearing age and in pregnancy. In adults, the course is more chronic although spontaneous remission can also occur within months of initial diagnosis. A thorough and timely workup of thrombocytopenia is imperative to rule out other differentials of ITP as it is considered a diagnosis of exclusion. Primary care physicians encounter patients who exhibit signs of thrombocytopenia such as petechiae or purpura on a regular basis. A high index of clinical suspicion is required to accurately diagnose ITP and commence the appropriate treatment including glucocorticoids to increase the chances of a favorable prognosis as described by the authors. |
first_indexed | 2024-04-11T02:24:11Z |
format | Article |
id | doaj.art-d958a6d6f7f347bd85d1b963b2a90a7b |
institution | Directory Open Access Journal |
issn | 2000-9666 |
language | English |
last_indexed | 2024-04-11T02:24:11Z |
publishDate | 2019-01-01 |
publisher | Greater Baltimore Medical Center |
record_format | Article |
series | Journal of Community Hospital Internal Medicine Perspectives |
spelling | doaj.art-d958a6d6f7f347bd85d1b963b2a90a7b2023-01-02T23:06:30ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662019-01-0191596110.1080/20009666.2019.15658841565884Immune thrombocytopenic purpuraAbir Zainal0Amr Salama1Richard Alweis2Unity Hospital, Rochester Regional HealthUnity Hospital, Rochester Regional HealthUnity Hospital, Rochester Regional HealthImmune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count <150,000 u/L), which is not associated with a systemic illness. ITP is reported in approximately 2 per 100,000 adults. The mean age of diagnosis is 50 years. ITP is more common in females of childbearing age and in pregnancy. In adults, the course is more chronic although spontaneous remission can also occur within months of initial diagnosis. A thorough and timely workup of thrombocytopenia is imperative to rule out other differentials of ITP as it is considered a diagnosis of exclusion. Primary care physicians encounter patients who exhibit signs of thrombocytopenia such as petechiae or purpura on a regular basis. A high index of clinical suspicion is required to accurately diagnose ITP and commence the appropriate treatment including glucocorticoids to increase the chances of a favorable prognosis as described by the authors.http://dx.doi.org/10.1080/20009666.2019.1565884Immune thrombocytopenic purpurahematologyplateletscorticosteroids |
spellingShingle | Abir Zainal Amr Salama Richard Alweis Immune thrombocytopenic purpura Journal of Community Hospital Internal Medicine Perspectives Immune thrombocytopenic purpura hematology platelets corticosteroids |
title | Immune thrombocytopenic purpura |
title_full | Immune thrombocytopenic purpura |
title_fullStr | Immune thrombocytopenic purpura |
title_full_unstemmed | Immune thrombocytopenic purpura |
title_short | Immune thrombocytopenic purpura |
title_sort | immune thrombocytopenic purpura |
topic | Immune thrombocytopenic purpura hematology platelets corticosteroids |
url | http://dx.doi.org/10.1080/20009666.2019.1565884 |
work_keys_str_mv | AT abirzainal immunethrombocytopenicpurpura AT amrsalama immunethrombocytopenicpurpura AT richardalweis immunethrombocytopenicpurpura |