VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies

Studies of the mechanism, kinetics and thermodynamic constants of VO2+ and Cu2+ Ceftriaxone and Ceftizoxime interactions at the pH range between pH 2 and 5 and at the temperatures of 30 º, 40 º, 50 º and 60 ºC, using reversed phase HPLC and ion exchange HPLC, are reported. The effects of pH, tempera...

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Main Authors: Doadrio Antonio L., Mayorga Antonio, Orenga Regina
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2002-01-01
Series:Journal of the Brazilian Chemical Society
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000100015
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author Doadrio Antonio L.
Mayorga Antonio
Orenga Regina
author_facet Doadrio Antonio L.
Mayorga Antonio
Orenga Regina
author_sort Doadrio Antonio L.
collection DOAJ
description Studies of the mechanism, kinetics and thermodynamic constants of VO2+ and Cu2+ Ceftriaxone and Ceftizoxime interactions at the pH range between pH 2 and 5 and at the temperatures of 30 º, 40 º, 50 º and 60 ºC, using reversed phase HPLC and ion exchange HPLC, are reported. The effects of pH, temperature and ion concentration on the hydrolysis reaction have been evaluated. HPLC studies provided satisfactory evidence of the reaction mechanism. Mechanisms for Cu2+ and VO2+ induced reactions involve a complex of 1:1 stoichiometry.
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spelling doaj.art-d95a192a1a7e449a8bdf7f17908b649d2022-12-22T01:53:54ZengSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society0103-50532002-01-0113195100VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic StudiesDoadrio Antonio L.Mayorga AntonioOrenga ReginaStudies of the mechanism, kinetics and thermodynamic constants of VO2+ and Cu2+ Ceftriaxone and Ceftizoxime interactions at the pH range between pH 2 and 5 and at the temperatures of 30 º, 40 º, 50 º and 60 ºC, using reversed phase HPLC and ion exchange HPLC, are reported. The effects of pH, temperature and ion concentration on the hydrolysis reaction have been evaluated. HPLC studies provided satisfactory evidence of the reaction mechanism. Mechanisms for Cu2+ and VO2+ induced reactions involve a complex of 1:1 stoichiometry.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000100015ceftriaxoneceftizoximecopper (II)vanadium (IV)
spellingShingle Doadrio Antonio L.
Mayorga Antonio
Orenga Regina
VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies
Journal of the Brazilian Chemical Society
ceftriaxone
ceftizoxime
copper (II)
vanadium (IV)
title VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies
title_full VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies
title_fullStr VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies
title_full_unstemmed VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies
title_short VO2+ and Cu2+ Interactions with Ceftriaxone and Ceftizoxime. HPLC Kinetic Studies
title_sort vo2 and cu2 interactions with ceftriaxone and ceftizoxime hplc kinetic studies
topic ceftriaxone
ceftizoxime
copper (II)
vanadium (IV)
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000100015
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