Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroco...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2018-05-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/24/5/17-1992_article |
| _version_ | 1819241480126988288 |
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| author | Regev Cohen Frida Babushkin Maurice Shapiro Martina Uda Yafit Atiya-Nasagi Dar Klein Talya Finn |
| author_facet | Regev Cohen Frida Babushkin Maurice Shapiro Martina Uda Yafit Atiya-Nasagi Dar Klein Talya Finn |
| author_sort | Regev Cohen |
| collection | DOAJ |
| description | We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis. |
| first_indexed | 2024-12-23T14:24:34Z |
| format | Article |
| id | doaj.art-d95b5eb8ab384a15beb7b05267f33cb4 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-23T14:24:34Z |
| publishDate | 2018-05-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-d95b5eb8ab384a15beb7b05267f33cb42022-12-21T17:43:42ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-05-0124583584010.3201/eid2405.171992Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, IsraelRegev CohenFrida BabushkinMaurice ShapiroMartina UdaYafit Atiya-NasagiDar KleinTalya FinnWe report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis.https://wwwnc.cdc.gov/eid/article/24/5/17-1992_articleIsraeli spotting feverRickettsia conorii subsp. israelensisrickettsiacase seriespurpura fulminansSharon District |
| spellingShingle | Regev Cohen Frida Babushkin Maurice Shapiro Martina Uda Yafit Atiya-Nasagi Dar Klein Talya Finn Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel Emerging Infectious Diseases Israeli spotting fever Rickettsia conorii subsp. israelensis rickettsia case series purpura fulminans Sharon District |
| title | Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel |
| title_full | Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel |
| title_fullStr | Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel |
| title_full_unstemmed | Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel |
| title_short | Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel |
| title_sort | two cases of israeli spotted fever with purpura fulminans sharon district israel |
| topic | Israeli spotting fever Rickettsia conorii subsp. israelensis rickettsia case series purpura fulminans Sharon District |
| url | https://wwwnc.cdc.gov/eid/article/24/5/17-1992_article |
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