Discovery of an Unusual Fatty Acid Amide from the ndgRyo Gene Mutant of Marine-Derived Streptomyces youssoufiensis

Discovery of an Unusual Fatty Acid Amide from the ndgRyo Gene Mutant of Marine-Derived Streptomyces youssoufiensis

NdgRyo, an IclR-like regulator, was selected as the target gene to activate new secondary metabolites in the marine-derived Streptomyces youssoufiensis OUC6819. Inactivation of the ndgRyo gene in S. youssoufiensis OUC6819 led to the accumulation of a new fatty acid amide (1), with an unusual 3-amino...

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Bibliographic Details
Main Authors: Jing Hou, Jing Liu, Lu Yang, Zengzhi Liu, Huayue Li, Qian Che, Tianjiao Zhu, Dehai Li, Wenli Li
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Marine Drugs
Subjects:
NdgRyo
IclR family regulator
Streptomyces
fatty acid amide
genome mining
Online Access:http://www.mdpi.com/1660-3397/17/1/12

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