Theissenolactone C Exhibited Ocular Protection of Endotoxin-Induced Uveitis by Attenuating Ocular Inflammatory Responses and Glial Activation

Theissenolactone C Exhibited Ocular Protection of Endotoxin-Induced Uveitis by Attenuating Ocular Inflammatory Responses and Glial Activation

The aim of this study was to investigate the effects of a natural component, theissenolactone C (LC53), on the ocular inflammation of experimental endotoxin-induced uveitis (EIU) and its related mechanisms in microglia. Evaluation of the severity of anterior uveitis indicated that LC53 treatment sig...

Full description

Bibliographic Details
Main Authors: Fan-Li Lin, Jau-Der Ho, Yu-Wen Cheng, George C. Y. Chiou, Jing-Lun Yen, Hung-Ming Chang, Tzong-Huei Lee, George Hsiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
endotoxin-induced uveitis
ocular inflammation
microglia
NF-κB
TNF-α
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00326/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00326/full

Similar Items